Lutrate Depot J Code: J1954

Drug & Product Overview

HCPCS Descriptor Injection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mg

HCPCS Added Date January 1, 2023

Manufacturer Avyxa Pharma

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit

About Lutrate Depot

Lutrate Depot is a medication aligned to the HCPCS J Code: J1954 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intramuscular route and manufactured by Avyxa Pharma.

According to CMS Drug Use Information: Leuprolide is used to treat advanced prostate cancer. It is not a cure. Most types of prostate cancer need the hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Package	Manufacturer	HCPCS Units	WAC	AWP
83831-0134-01	Kit Lutrate Depot Kit - 1 KIT in 1 CARTON (83831-134-01) * 2 mL in 1 VIAL, SINGLE-DOSE (83831-150-22) * 2 mL in 1 SYRINGE (83831-135-02)	Avyxa Pharma, LLC	3	$2,000.00 $666.667 / unit	$2,400.00 $800.00 / unit

Effective 3/26/25 (WAC & AWP)

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Lutrate Depot Pricing & Reimbursement

J1954 Private Payer Reimbursement

$726.50 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

NDC Package

HCPCS Units

Markup / Markdown

%

Common:

Estimates only. Payer reimbursement varies by contract, site of care, and sequestration.

Estimated Reimbursement

Leuprolide Acetate 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J1950	AbbVie	Leuprolide Acetate	Injection, leuprolide acetate (for depot suspension), per 3.75 mg
J1951	Tolmar Pharmaceuticals	Leuprolide Acetate	Injection, leuprolide acetate for depot suspension (fensolvi), 0.25 mg
J1952	Accord	Leuprolide Acetate	Leuprolide injectable, camcevi, 1 mg
J1954	Generic Code (Multiple Manufacturers)	Leuprolide Acetate	Injection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mg
J9217	Generic Code (Multiple Manufacturers)	Leuprolide Acetate	Leuprolide acetate (for depot suspension), 7.5 mg

Lutrate Depot Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 28.22%

Avg. Days to File 8.5days

Avg. Days to Pay 25.2days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J1954 claims analytics on FocalPoint →

Lutrate Depot CPT Administration Codes

CPT Code	Description
96402	Chemotherapy administration, subcutaneous or intramuscular; hormonal anti-neoplastic

JW / JZ modifiers apply

CMS has identified Lutrate Depot (J1954) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

Lutrate Depot Medically Unlikely Edits (MUE)

The most billing units of J1954 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 7.5 mg.

Practitioner Office & Hospital Outpatient

3 units / day

= 22.5 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Lutrate Depot Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Advanced prostate cancer

Frequently Asked Questions

Is there an available Lutrate Depot billing and coding guide?

We have not yet identified a manufacturer source of Lutrate Depot billing and coding information.

Are there any available Leuprollide Depot patient assistance programs?

Lutrate Depot patient assistance can be found through AvyxaAssist Visit Here →

Where can I find Lutrate Depot prescribing information?

Lutrate Depot prescribing information can be found at the link below: Visit Here →

Where can I find Lutrate Depot side effect information?

Our team has not yet identified a source of side effects information for Lutrate Depot. Please check back in a few weeks.

Does billing Lutrate Depot require JZ/JW wastage modifiers?

CMS has identified Lutrate Depot(J1954) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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