Home Drug Codes J Codes J2353 · SANDOSTATIN LAR DEPOT
Updated July 1st, 2026

SANDOSTATIN LAR DEPOT J Code: J2353

Injection, octreotide, depot form for intramuscular injection, 1 mg

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Q4 2026 Medicare Payment Limit for J2353, effective October 1, 2026: $211.321 per HCPCS billing unit, up 1.6% from $208.095. From CMS's final file.

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Medicare Payment Limit ?
$208.095
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$208.095
/ HCPCS billing unit · APC 1207
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
12
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Drug & Product Overview

HCPCS Descriptor Injection, octreotide, depot form for intramuscular injection, 1 mg
HCPCS Added Date January 1, 2004
Manufacturer Multiple Manufacturers
Route of Administration Intramuscular
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Kit | Not Available

About SANDOSTATIN LAR DEPOT

Sandostatin LAR Depot is a medication aligned to the HCPCS J Code: J2353 for billing, pricing, and reimbursement purposes in the United States. It is a Growth Disorder drug administered via the intramuscular route and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is a long-acting form of octreotide. Octreotide is used to treat severe watery diarrhea and sudden reddening of the face and neck caused by certain types of tumors (such as carcinoid tumors, vasoactive intestinal peptide tumors) that are found usually in the intestines and pancreas. The symptoms occur when these tumors make too much of certain natural substances (hormones). This medication works by blocking the production of these hormones. By decreasing watery diarrhea, octreotide helps to reduce the loss of body fluids and minerals. Octreotide is also used to treat a certain condition (acromegaly) that occurs when the body makes too much of a certain natural substance called growth hormone. Treating acromegaly helps reduce the risk of serious problems such as diabetes and heart disease. Octreotide works by decreasing how much growth hormone your body makes. This drug is not a cure for these conditions. This medication is usually used with other treatment (such as surgery, radiation, other drugs).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 12 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00078-0811-81 Sandostatin LAR Depot Novartis Pharmaceuticals Corporation 10 Kit
00078-0818-81 Sandostatin LAR Depot Novartis Pharmaceuticals Corporation 20 Kit
00078-0825-81 Sandostatin LAR Depot Novartis Pharmaceuticals Corporation 30 Kit
00480-9257-08 Octreotide Acetate Teva Pharmaceuticals, Inc. 10 Kit
67457-0756-10 Octreotide Acetate Mylan Institutional LLC 10 Kit
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SANDOSTATIN LAR DEPOT Pricing & Reimbursement

J2353 Private Payer Reimbursement
$207.34 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

SANDOSTATIN LAR DEPOT CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
JW / JZ modifiers apply

CMS has identified Sandostatin LAR Depot (J2353) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

SANDOSTATIN LAR DEPOT Medically Unlikely Edits (MUE)

The most billing units of J2353 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
60 units / day
= 60 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

SANDOSTATIN LAR DEPOT Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acromegaly Carcinoid Tumors Vasoactive Intestinal Peptide Tumors (VIPomas)

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Frequently Asked Questions

Is there an available Sandostatin Lar Depot billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for SANDOSTATIN LAR DEPOT.
Are there any available Sandostatin Lar Depot patient assistance programs?
SANDOSTATIN LAR DEPOT patient assistance information can be found through Multiple Manufacturers. Visit Here →
Where can I find Sandostatin Lar Depot prescribing information?
SANDOSTATIN LAR DEPOT prescribing information can be found at the link below: Visit Here →
Where can I find Sandostatin Lar Depot side effect information?
Information regarding SANDOSTATIN LAR DEPOT's side effects can be found at MedlinePlus Visit Here →
Does billing SANDOSTATIN LAR DEPOT require JZ/JW wastage modifiers?
CMS has identified SANDOSTATIN LAR DEPOT(J2353) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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