SIGNIFOR LAR J Code: J2502

Drug & Product Overview

HCPCS Descriptor Injection, pasireotide long acting, 1 mg

HCPCS Added Date January 1, 2016

Manufacturer Recordati Rare Diseases

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit

About SIGNIFOR LAR

Signifor LAR is a medication aligned to the HCPCS J Code: J2502 for billing, pricing, and reimbursement purposes in the United States. This Growth Disorder medication is administered via the intramuscular route and manufactured by Recordati Rare Diseases.

According to CMS Drug Use Information: Pasireotide is used to treat a certain condition (acromegaly) that occurs when the body makes too much of a certain natural substance called growth hormone. Treating acromegaly helps reduce the risk of serious problems such as diabetes and heart disease. Pasireotide works by decreasing the amount of growth hormone made in the body. Pasireotide is also used to treat a certain condition (Cushing's disease) when surgery has not been fully successful or cannot be used to correct the condition. Cushing's disease occurs when the body makes too much of a certain hormone called cortisol. Having too much cortisol in the body may lead to high blood pressure, high blood sugar, and other problems. Pasireotide works by decreasing the amount of cortisol made in the body.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
55292-0139-01	Signifor LAR	Recordati Rare Diseases, Inc.	10	Kit
55292-0140-01	Signifor LAR	Recordati Rare Diseases, Inc.	20	Kit
55292-0141-01	Signifor LAR	Recordati Rare Diseases, Inc.	30	Kit
55292-0142-01	Signifor LAR	Recordati Rare Diseases, Inc.	40	Kit
55292-0143-01	Signifor LAR	Recordati Rare Diseases, Inc.	60	Kit

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SIGNIFOR LAR Pricing & Reimbursement

J2502 Private Payer Reimbursement

$579.93 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

SIGNIFOR LAR CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

CMS does not include Signifor LAR (J2502) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2502. Wastage billing guide →

SIGNIFOR LAR Medically Unlikely Edits (MUE)

The most billing units of J2502 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

60 units / day

= 60 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

SIGNIFOR LAR Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acromegaly Cushing's Disease

Frequently Asked Questions

Is there an available Signifor Lar billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for SIGNIFOR LAR.

Are there any available Signifor Lar patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for SIGNIFOR LAR.

Where can I find Signifor Lar prescribing information?

SIGNIFOR LAR prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Signifor Lar side effect information?

Our team has not yet identified a source of side effects information for SIGNIFOR LAR. Please check back in a few weeks.

Does billing SIGNIFOR LAR require JZ/JW wastage modifiers?

CMS does not include SIGNIFOR LAR (J2502) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2502. For more information, visit the link below.

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