ETOPOSIDE J Code: J8560

Drug & Product Overview

HCPCS Descriptor Etoposide; oral, 50 mg

HCPCS Added Date January 1, 1995

Manufacturer Mylan Pharmaceuticals

Route of Administration Oral

Generic Status Single-Source; Branded

Dosage Form Capsule

About ETOPOSIDE

Etoposide is a medication aligned to the HCPCS J Code: J8560 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the oral route and manufactured by Mylan Pharmaceuticals.

According to CMS Drug Use Information: Etoposide is used to treat certain forms of lung cancer (such as small cell lung cancer). Etoposide works by slowing the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00378-3266-94	Etoposide	Mylan Pharmaceuticals Inc.	20	50 MG

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ETOPOSIDE Pricing & Reimbursement

J8560 Private Payer Reimbursement

$89.05 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

ETOPOSIDE CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
96409 Login for More	Chemotherapy administration; intravenous, push technique, single or initial substance/drug Login for More
96417 Login for More	Chemotherapy administration, intravenous infusion technique; each additional sequential infusion (different substance/drug) up to 1 hour (List separately in addition to code for primary procedure) Login for More

Not on the CMS JW / JZ list

CMS does not include Etoposide (J8560) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J8560. Wastage billing guide →

ETOPOSIDE Medically Unlikely Edits (MUE)

The most billing units of J8560 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 50 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

0 units / day

Not payable in this setting

Hospital Outpatient

6 units / day

= 300 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ETOPOSIDE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Small Cell Lung Cancer

Drug Class

Topoisomerase Inhibitor [EPC]Topoisomerase Inhibitors [MoA]

Frequently Asked Questions

Is there an available Etoposide billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for ETOPOSIDE.

Are there any available Etoposide patient assistance programs?

ETOPOSIDE patient assistance information can be found through Mylan. Visit Here →

Where can I find Etoposide prescribing information?

ETOPOSIDE prescribing information can be found at the link below: Visit Here →

Where can I find Etoposide side effect information?

Information regarding ETOPOSIDE's side effects can be found at MedlinePlus Visit Here →

Does billing ETOPOSIDE require JZ/JW wastage modifiers?

CMS does not include ETOPOSIDE (J8560) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J8560. For more information, visit the link below.

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