HYCAMTIN J Code: J8705

Drug & Product Overview

HCPCS Descriptor Topotecan, oral, 0.25 mg

HCPCS Added Date January 1, 2009

Manufacturer Sandoz

Route of Administration Oral

Generic Status Single-Source; Branded

Dosage Form Capsule

About HYCAMTIN

Hycamtin is a medication aligned to the HCPCS J Code: J8705 for billing, pricing, and reimbursement purposes in the United States. Classified under Oncology, it is administered via the oral route and manufactured by Sandoz.

According to CMS Drug Use Information: This medication is used to treat small cell lung cancer. It works by killing cancer cells or slowing their growth.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00078-0672-01	Hycamtin	Sandoz Inc.	10	0.25 MG
00078-0673-01	Hycamtin	Sandoz Inc.	40	1 MG
66758-0101-11	Hycamtin	Sandoz Inc	10	.25 MG
66758-0102-11	Hycamtin	Sandoz Inc	40	1 MG

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HYCAMTIN Pricing & Reimbursement

J8705 Private Payer Reimbursement

$128.61 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

HYCAMTIN CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
96409 Login for More	Chemotherapy administration; intravenous, push technique, single or initial substance/drug Login for More
96411 Login for More	Chemotherapy administration; intravenous, push technique, each additional substance/drug (List separately in addition to code for primary procedure) Login for More
96417 Login for More	Chemotherapy administration, intravenous infusion technique; each additional sequential infusion (different substance/drug) up to 1 hour (List separately in addition to code for primary procedure) Login for More
96416 Login for More	Chemotherapy administration, IV infusion technique; initiation of prolonged chemotherapy infusion (more than 8 hours) requiring use of a portable or implantable pump Login for More

Not on the CMS JW / JZ list

CMS does not include Hycamtin (J8705) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J8705. Wastage billing guide →

HYCAMTIN Medically Unlikely Edits (MUE)

The most billing units of J8705 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.25 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

0 units / day

Not payable in this setting

Hospital Outpatient

22 units / day

= 5.5 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

HYCAMTIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Relapsed small cell lung cancer (SCLC)

Drug Class

Topoisomerase Inhibitor [EPC]Topoisomerase Inhibitors [MoA]

Frequently Asked Questions

Is there an available Hycamtin billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for HYCAMTIN.

Are there any available Hycamtin patient assistance programs?

HYCAMTIN patient assistance information can be found through Novartis. Visit Here →

Where can I find Hycamtin prescribing information?

HYCAMTIN prescribing information can be found at the link below: Visit Here →

Where can I find Hycamtin side effect information?

Information regarding HYCAMTIN's side effects can be found at MedlinePlus Visit Here →

Does billing HYCAMTIN require JZ/JW wastage modifiers?

CMS does not include HYCAMTIN (J8705) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J8705. For more information, visit the link below.

About BuyandBill.com:

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