MITOXANTRONE HCL J Code: J9293

Drug & Product Overview

HCPCS Descriptor Injection, mitoxantrone hydrochloride, per 5 mg

HCPCS Added Date January 1, 1990

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Multi-Dose

Dosage Form Injection, Solution | Injection, Solution, Concentrate

About MITOXANTRONE HCL

Mitoxantrone HCL is a medication aligned to the HCPCS J Code: J9293 for billing, pricing, and reimbursement purposes in the United States. Classified under Oncology, it is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Mitoxantrone is used to treat leukemia and other cancers. It is also used to treat multiple sclerosis. It belongs to a class of drugs known as anthracenediones and works by slowing or stopping the growth of certain cells (including cancer cells and cells that affect the body's natural defenses).

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 8 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
61703-0343-18	Mitoxantrone	Hospira, Inc.	4	20 MG / 10 ML
61703-0343-65	Mitoxantrone	Hospira, Inc.	5	25 MG / 12.5 ML
61703-0343-66	Mitoxantrone	Hospira, Inc.	6	30 MG / 15 ML
63323-0132-10	Mitoxantrone	Fresenius Kabi USA, LLC	4	20 MG / 10 ML
71288-0178-10	mitoXANTRONE	Meitheal Pharmaceuticals Inc.	4	20 MG / 10 ML
•••••-••••-•• Log in to view	MITOXANTRONE HCL
	MITOXANTRONE HCL
	MITOXANTRONE HCL

Login to view 3 more NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

MITOXANTRONE HCL Pricing & Reimbursement

J9293 Private Payer Reimbursement

$31.48 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

MITOXANTRONE HCL Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 31.75%

Avg. Days to File 16.1days

Avg. Days to Pay 29.5days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9293 claims analytics on FocalPoint →

MITOXANTRONE HCL CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

CMS does not include Mitoxantrone HCL (J9293) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9293. Wastage billing guide →

MITOXANTRONE HCL Medically Unlikely Edits (MUE)

The most billing units of J9293 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 5 mg.

Practitioner Office & Hospital Outpatient

8 units / day

= 40 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

MITOXANTRONE HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Nonlymphocytic Leukemia (ANLL) Hormone-Refractory Prostate Cancer Multiple Sclerosis

Drug Class

Topoisomerase Inhibitor [EPC]Topoisomerase Inhibitors [MoA]

Frequently Asked Questions

Is there an available Mitoxantrone Hcl billing and coding guide?

We have not yet identified a manufacturer source of Mitoxantrone Hcl billing and coding information.

Are there any available Mitoxantrone Hcl patient assistance programs?

Our team did not identify a source for Mitoxantrone Hcl patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Mitoxantrone Hcl prescribing information?

Our team is still working to identify a prescribing information source for MITOXANTRONE HCL

Where can I find Mitoxantrone Hcl side effect information?

Our team has not yet identified a source of side effects information for MITOXANTRONE HCL. Please check back in a few weeks.

Does billing MITOXANTRONE HCL require JZ/JW wastage modifiers?

CMS does not include MITOXANTRONE HCL (J9293) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9293. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.