Home › Drug Codes › J Codes › J9181 · ETOPOPHOS
Updated October 1st, 2026

ETOPOPHOS J Code: J9181

Injection, etoposide, 10 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q4 2026
APC Payment Limit ?
Not published
CMS publishes none for Q4 2026
ASP ?
No current ASP
Not available for Q4 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
21
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Drug & Product Overview

HCPCS Descriptor Injection, etoposide, 10 mg
HCPCS Added Date January 1, 1987
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status HCPCS Discontinued
Dosage Type Single-Dose, Multi-Dose
Dosage Form Injection | Injection, Powder, Lyophilized, For Solution | Injection, Solution | Injection, Solution, Concentrate | Not Available

About ETOPOPHOS

Etopophos is a medication aligned to the HCPCS J Code: J9181 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Etoposide is used to treat testicular cancer and certain forms of lung cancer (such as small cell lung cancer). Etoposide works by slowing the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

21 NDC packages are crosswalked to J9181. Package detail is available to logged-in subscribers.

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ETOPOPHOS Pricing & Reimbursement

J9181 Private Payer Reimbursement
$1.33 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

ETOPOPHOS CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Etopophos (J9181) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9181. Wastage billing guide →

ETOPOPHOS Medically Unlikely Edits (MUE)

The most billing units of J9181 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg.

Practitioner Office & Hospital Outpatient
100 units / day
= 1,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

ETOPOPHOS Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Refractory Testicular Tumors Small Cell Lung Cancer
Drug Class
Topoisomerase Inhibitor [EPC]Topoisomerase Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Etopophos billing and coding guide?
We have not yet identified a manufacturer source of Etopophos billing and coding information.
Are there any available Etopophos patient assistance programs?
Our team did not identify a source for Etopophos patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Etopophos prescribing information?
ETOPOPHOS prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Etopophos side effect information?
Our team has not yet identified a source of side effects information for ETOPOPHOS. Please check back in a few weeks.
Does billing ETOPOPHOS require JZ/JW wastage modifiers?
CMS does not include ETOPOPHOS (J9181) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9181. For more information, visit the link below.

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