Home › Drug Codes › Q Codes › Q2050 · DOXIL
Updated July 1st, 2026

DOXIL Q Code: Q2050

Injection, doxorubicin hydrochloride, liposomal, not otherwise specified, 10 mg

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Q4 2026 Medicare Payment Limit for Q2050, effective October 1, 2026: $97.823 per HCPCS billing unit, down 16.1% from $116.605. From CMS's final file.

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Medicare Payment Limit ?
$116.605
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$116.605
/ HCPCS billing unit · APC 7046
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
30
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Drug & Product Overview

HCPCS Descriptor Injection, doxorubicin hydrochloride, liposomal, not otherwise specified, 10 mg
HCPCS Added Date July 1, 2013
Manufacturer Multiple Manufacturers
Route of Administration Intravenous, Intravitreal
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injectable, Liposomal | Injection, Suspension, Liposomal | Not Available

About DOXIL

Doxil is a medication aligned to the HCPCS Q Code: Q2050 for billing, pricing, and reimbursement purposes in the United States. Classified under Oncology, it is administered via the intravenous or intravitreal routes and manufactured by multiple companies.

According to CMS Drug Use Information: Liposomal doxorubicin is an anthracycline-type chemotherapy drug that is used to treat certain types of cancer (such as ovarian cancer, AIDS-related Kaposi's sarcoma, multiple myeloma). It works by slowing or stopping cancer cell growth.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 30 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00338-0063-01 Doxil Baxter Healthcare Company 2 20 MG / 10 ML
00338-9665-01 Doxil Baxter Healthcare Corporation 5 50 MG / 25 ML
16714-0742-01 Doxorubicin HCl, Liposomal Northstar RxLLC 2 20 MG / 10 ML
25021-0263-10 Doxorubicin Hydrochloride Liposome Sagent Pharmaceuticals 2 20 MG / 10 ML
43598-0283-35 Doxorubicin HCl, Liposomal Dr. Reddy's Laboratories Inc. 2 2 MG
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DOXIL Pricing & Reimbursement

Q2050 Private Payer Reimbursement
$110.83 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

DOXIL Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 13.99%
Avg. Days to File 10.1days
Avg. Days to Pay 25.4days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore Q2050 claims analytics on FocalPoint →
OnPoint Oncology

DOXIL CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Doxil (Q2050) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q2050. Wastage billing guide →

DOXIL Medically Unlikely Edits (MUE)

The most billing units of Q2050 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
14 units / day
= 140 mg per day
Hospital Outpatient
20 units / day
= 200 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

DOXIL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

AIDS-Related Kaposi's Sarcoma Multiple Myeloma Ovarian Cancer
Drug Class
Anthracycline Topoisomerase Inhibitor [EPC]Anthracyclines [CS]Topoisomerase Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Doxil billing and coding guide?
We have not yet identified a manufacturer source of Doxil billing and coding information.
Are there any available Doxil patient assistance programs?
Our team did not identify a source for Doxil patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Doxil prescribing information?
DOXIL prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Doxil side effect information?
Our team has not yet identified a source of side effects information for DOXIL. Please check back in a few weeks.
Does billing DOXIL require JZ/JW wastage modifiers?
CMS does not include DOXIL (Q2050) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q2050. For more information, visit the link below.

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