Home Drug Codes J Codes J9000 · ADRIAMYCIN
Updated July 1st, 2026

ADRIAMYCIN J Code: J9000

Injection, doxorubicin hydrochloride, 10 mg

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Q4 2026 Medicare Payment Limit for J9000, effective October 1, 2026: $3.12 per HCPCS billing unit, up 15.1% from $2.71. From CMS's final file.

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Medicare Payment Limit ?
$2.71
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
46
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Drug & Product Overview

HCPCS Descriptor Injection, doxorubicin hydrochloride, 10 mg
HCPCS Added Date January 1, 1984
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose, Multi-Dose
Dosage Form Injection, Powder, Lyophilized, For Solution | Injection, Solution | Not Available

About ADRIAMYCIN

Adriamycin is a medication aligned to the HCPCS J Code: J9000 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Doxorubicin is an anthracycline type of chemotherapy that is used to treat several different types of cancer. Doxorubicin works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 46 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00069-0255-10 Doxorubicin Hydrochloride Pfizer Laboratories Div Pfizer Inc 2 20 MG / 10 ML
00069-3030-20 Doxorubicin HCl Pfizer Inc 1 2 MG
00143-9084-01 Doxorubicin Hydrochloride Hikma Pharmaceuticals USA Inc. 1 10 MG / 5 ML
16714-0001-01 Doxorubicin HCl Northstar RxLLC 20 2 MG
25021-0207-05 Doxorubicin HCl Sagent Pharmaceuticals 10 10 MG / 5 ML
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ADRIAMYCIN Pricing & Reimbursement

J9000 Private Payer Reimbursement
$3.38 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

ADRIAMYCIN Claims Performance

Claims from Jan 2026 – Aug 2026
Claim Denial Rate 9.72%
Avg. Days to File 11.5days
Avg. Days to Pay 25.8days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9000 claims analytics on FocalPoint →
OnPoint Oncology

ADRIAMYCIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Adriamycin (J9000) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9000. Wastage billing guide →

ADRIAMYCIN Medically Unlikely Edits (MUE)

The most billing units of J9000 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg.

Practitioner Office & Hospital Outpatient
20 units / day
= 200 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

ADRIAMYCIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Lymphoblastic Leukemia Acute Myeloblastic Leukemia Breast Cancer Disseminated neoplastic conditions (acute lymphoblastic leukemia, acute myeloblastic leukemia, Wilms' tumor, neuroblastoma, soft tissue and bone sarcomas, breast carcinoma, ovarian carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, gastric carcinoma, Hodgkin's disease, malignant lymphoma, bronchogenic carcinoma) Early breast cancer with axillary lymph node involvement Hodgkin Lymphoma Hodgkin lymphoma Metastatic Bone Sarcoma Metastatic Breast Cancer Metastatic Bronchogenic Carcinoma Metastatic Disease, Leukemia, or Lymphoma Metastatic Gastric Carcinoma Metastatic Neuroblastoma Metastatic Ovarian Carcinoma Metastatic Soft Tissue Sarcoma Metastatic Thyroid Carcinoma Metastatic Transitional Cell Bladder Carcinoma Metastatic Wilms' Tumor Non-Hodgkin Lymphoma acute lymphoblastic leukemia acute myeloblastic leukemia axillary lymph node-positive breast cancer metastatic Wilms' tumor metastatic bone sarcoma metastatic breast cancer metastatic bronchogenic carcinoma metastatic gastric carcinoma metastatic neuroblastoma metastatic ovarian carcinoma metastatic soft tissue sarcoma metastatic thyroid carcinoma metastatic transitional cell bladder carcinoma non-Hodgkin lymphoma
Drug Class
Anthracycline Topoisomerase Inhibitor [EPC]Anthracyclines [CS]Topoisomerase Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Adriamycin billing and coding guide?
We have not yet identified a manufacturer source of Adriamycin billing and coding information.
Are there any available Adriamycin patient assistance programs?
Our team did not identify a source for Adriamycin patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Adriamycin prescribing information?
ADRIAMYCIN prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Adriamycin side effect information?
Our team has not yet identified a source of side effects information for ADRIAMYCIN. Please check back in a few weeks.
Does billing ADRIAMYCIN require JZ/JW wastage modifiers?
CMS does not include ADRIAMYCIN (J9000) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9000. For more information, visit the link below.

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