BORUZU J Code: J9054

Drug & Product Overview

HCPCS Descriptor Injection, bortezomib (boruzu), 0.1 mg

HCPCS Added Date April 1, 2025

Manufacturer Amneal Biosciences

Route of Administration Intravenous, Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection

About BORUZU

Boruzu is a medication aligned to the HCPCS J Code: J9054 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intravenous or subcutaneous routes and manufactured by Amneal Biosciences.

According to CMS Drug Use Information: This medication is used to treat certain types of cancer (such as multiple myeloma, mantle cell lymphoma). It works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
70121-2484-01	Boruzu	Amneal Pharmaceuticals LLC	35	3.5 MG / 1.4 ML

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BORUZU Pricing & Reimbursement

J9054 Private Payer Reimbursement

$26.33 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Bortezomib 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J9041	Generic Code (Multiple Manufacturers)	Bortezomib	Injection, bortezomib, 0.1 mg
J9046	Dr Reddy's Laboratories, Inc	Bortezomib	Injection, bortezomib (dr. reddy's), not therapeutically equivalent to j9041, 0.1 mg
J9048	Fresenius Kabi	Bortezomib	Injection, bortezomib (fresenius kabi), not therapeutically equivalent to j9041, 0.1 mg
J9049	Hospira	Bortezomib	Injection, bortezomib (hospira), not therapeutically equivalent to j9041, 0.1 mg
J9051	Fosun Pharma	Bortezomib	Injection, bortezomib (maia), not therapeutically equivalent to j9041, 0.1 mg
J9054	Amneal Biosciences	Bortezomib	Injection, bortezomib (boruzu), 0.1 mg

BORUZU Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 4.73%

Avg. Days to File 4.5days

Avg. Days to Pay 21.7days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J9054 claims analytics on FocalPoint →

BORUZU CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

BORUZU Medically Unlikely Edits (MUE)

The most billing units of J9054 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

70 units / day

= 7 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

BORUZU Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Mantle Cell Lymphoma Multiple Myeloma

Drug Class

Proteasome Inhibitor [EPC]Proteasome Inhibitors [MoA]

Frequently Asked Questions

Is there a manufacturer-published BORUZU billing and coding guide?

Billing and coding information for BORUZU can be found through AMNEAL BIOSCIENCES. Visit Here →

What are the available BORUZU patient assistance programs?

BORUZU patient assistance information can be found through AMNEAL BIOSCIENCES. Visit Here →

Where can I find BORUZU prescribing information?

Our team has not identified a source of prescribing information for BORUZU.

Where can I find BORUZU side effect information?

Our team has not identified a source of side effect information for BORUZU.

Does billing BORUZU require JZ/JW wastage modifiers?

CMS does not include BORUZU (J9054) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9054. For more information, visit the link below.

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