Bortezomib J Code: J9049

Drug & Product Overview

HCPCS Descriptor Injection, bortezomib (hospira), not therapeutically equivalent to j9041, 0.1 mg

HCPCS Added Date January 1, 2023

Manufacturer Multiple Manufacturers

Route of Administration Intravenous, Subcutaneous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About Bortezomib

Bortezomib is a medication aligned to the HCPCS J Code: J9049 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous or subcutaneous routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to treat certain types of cancer (such as multiple myeloma, mantle cell lymphoma). It works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 2 of 3 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00409-1703-01	Bortezomib	Hospira, Inc.	25	2.5 MG
00409-1704-01	Bortezomib	Hospira, Inc.	10	1 MG
•••••-••••-•• Log in to view	Bortezomib

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Bortezomib Pricing & Reimbursement

J9049 Private Payer Reimbursement

$1.40 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Bortezomib 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J9041	Generic Code (Multiple Manufacturers)	Bortezomib	Injection, bortezomib, 0.1 mg
J9046	Dr Reddy's Laboratories, Inc	Bortezomib	Injection, bortezomib (dr. reddy's), not therapeutically equivalent to j9041, 0.1 mg
J9048	Fresenius Kabi	Bortezomib	Injection, bortezomib (fresenius kabi), not therapeutically equivalent to j9041, 0.1 mg
J9049	Hospira	Bortezomib	Injection, bortezomib (hospira), not therapeutically equivalent to j9041, 0.1 mg
J9051	Fosun Pharma	Bortezomib	Injection, bortezomib (maia), not therapeutically equivalent to j9041, 0.1 mg
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Bortezomib CPT Administration Codes

CPT Code	Description
96401	Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Login for More	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure) Login for More

JW / JZ modifiers apply

CMS has identified Bortezomib (J9049) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

Bortezomib Medically Unlikely Edits (MUE)

The most billing units of J9049 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

35 units / day

= 3.5 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Bortezomib Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Mantle Cell Lymphoma Multiple Myeloma

Drug Class

Proteasome Inhibitor [EPC]Proteasome Inhibitors [MoA]

Frequently Asked Questions

Is there an available Bortezomib billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for Bortezomib.

Are there any available Bortezomib patient assistance programs?

Bortezomib patient assistance information can be found through Pfizer. Visit Here →

Where can I find Bortezomib prescribing information?

Bortezomib prescribing information can be found at the link below: Visit Here →

Where can I find Bortezomib side effect information?

Information regarding Bortezomib's side effects can be found at MedlinePlus Visit Here →

Does billing Bortezomib require JZ/JW wastage modifiers?

CMS has identified Bortezomib(J9049) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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