Home › Drug Codes › J Codes › J3424 · Cyanokit
Updated October 1st, 2026

Cyanokit J Code: J3424

Injection, hydroxocobalamin, intravenous, 25 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q4 2026
APC Payment Limit ?
$5.443
/ HCPCS billing unit · APC 0740
ASP ?
No current ASP
Not available for Q4 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, hydroxocobalamin, intravenous, 25 mg
HCPCS Added Date April 1, 2024
Manufacturer BTG International
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Form Injection, Powder, Lyophilized, For Solution

About Cyanokit

Cyanokit is a medication aligned to the HCPCS J Code: J3424 for billing, pricing, and reimbursement purposes in the United States. It is a Hematology drug administered via the intravenous route and manufactured by BTG International.

Manufacturers, reach out to us to add more information.

NDC Code Information

2 NDC packages are crosswalked to J3424. Package detail is available to logged-in subscribers.

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Cyanokit Pricing & Reimbursement

J3424 Private Payer Reimbursement
$5.23 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Hydroxocobalamin 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J3424 Generic Code (Multiple Manufacturers) Hydroxocobalamin Injection, hydroxocobalamin, intravenous, 25 mg
J3425 Teva Hydroxocobalamin Injection, hydroxocobalamin, intramuscular, 10 mcg

Cyanokit CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

Cyanokit Medically Unlikely Edits (MUE)

The most billing units of J3424 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 25 mg.

Practitioner Office & Hospital Outpatient
400 units / day
= 10,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

Cyanokit Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

cyanide poisoning
Drug Class
Antidote [EPC]

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Frequently Asked Questions

Is there an available Cyanokit billing and coding guide?
Billing and coding information for Cyanokit can be found through SERB Pharmaceuticals. Visit Here →
Are there any available Cyanokit patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for Cyanokit.
Where can I find Cyclophosphamide (Sandoz) prescribing information?
Cyanokit prescribing information can be found at the link below: Visit Here →
Where can I find Cyanokit side effect information?
Our team has not yet identified a source of side effect information for Cyanokit.
Does billing Cyanokit require JZ/JW wastage modifiers?
CMS does not include Cyanokit (J3424) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3424. For more information, visit the link below.

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