Home Drug Codes J Codes J1451 · FOMEPIZOLE
Updated July 1st, 2026

FOMEPIZOLE J Code: J1451

Injection, fomepizole, 15 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
$6.184
/ HCPCS billing unit · APC 1689
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
4
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Drug & Product Overview

HCPCS Descriptor Injection, fomepizole, 15 mg
HCPCS Added Date January 1, 2006
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection | Injection, Solution

About FOMEPIZOLE

Fomepizole is a medication aligned to the HCPCS J Code: J1451 for billing, pricing, and reimbursement purposes in the United States. Classified under Misc., it is administered via the intravenous route and manufactured by multiple companies.

Manufacturers, reach out to us to add more information.

NDC Code Information

4 NDC packages are crosswalked to J1451. Package detail is available to logged-in subscribers.

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FOMEPIZOLE Pricing & Reimbursement

J1451 Private Payer Reimbursement
$12.48 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

FOMEPIZOLE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
JW / JZ modifiers apply

CMS has identified Fomepizole (J1451) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

FOMEPIZOLE Medically Unlikely Edits (MUE)

The most billing units of J1451 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 15 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office
1 unit / day
= 15 mg per day
Hospital Outpatient
200 units / day
= 3,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

FOMEPIZOLE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Ethylene glycol or methanol poisoning ethylene glycol or methanol poisoning
Drug Class
Antidote [EPC]

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Frequently Asked Questions

Is there an available Fomepizole billing and coding guide?
We have not yet identified a manufacturer source of Fomepizole billing and coding information.
Are there any available Fomepizole patient assistance programs?
Our team did not identify a source for Fomepizole patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Fomepizole prescribing information?
Our team is still working to identify a prescribing information source for FOMEPIZOLE
Where can I find Fomepizole side effect information?
Our team has not yet identified a source of side effects information for FOMEPIZOLE. Please check back in a few weeks.
Does billing FOMEPIZOLE require JZ/JW wastage modifiers?
CMS has identified FOMEPIZOLE(J1451) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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