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Updated October 1st, 2026

AHZANTIVE Q Code: Q5150

Injection, aflibercept-mrbb (ahzantive), biosimilar, 1 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q4 2026
APC Payment Limit ?
Not published
CMS publishes none for Q4 2026
ASP ?
No current ASP
Not available for Q4 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
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Drug & Product Overview

HCPCS Descriptor Injection, aflibercept-mrbb (ahzantive), biosimilar, 1 mg
HCPCS Added Date April 1, 2025
Manufacturer Formycon AG
Route of Administration Intravitreal
Generic Status Single-Source; Branded

About AHZANTIVE

Ahzantive is a medication aligned to the HCPCS Q Code: Q5150 for billing, pricing, and reimbursement purposes in the United States. This Ophthalmology medication is administered via the intravitreal route and manufactured by Formycon AG.

Manufacturers, reach out to us to add more information.

NDC Code Information

No NDC packages are aligned to Q5150 in publicly available CMS files.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
No public NDC alignments
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AHZANTIVE Pricing & Reimbursement

Q5150 Private Payer Reimbursement
$16.67 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Aflibercept Biosimilar Information:

AHZANTIVE Approval Date: June 28, 2024

Product Name HCPCS Code Active Ingredient BLA Type
Eylea J0178 Aflibercept 351(a) Originator Product
Opuviz Q5153 Aflibercept 351(k) Interchangeable
Yesafili Q5155 Aflibercept 351(k) Interchangeable
Ahzantive Q5150 Aflibercept 351(k) Interchangeable
Enzeevu Q5149 Aflibercept 351(k) Interchangeable
Pavblu Q5147 Aflibercept 351(k) Interchangeable
Eydenzelt Q5170 Aflibercept 351(k) Biosimilar
One of 6 Eylea biosimilars FDA-approved since 2024 See each approval by month on the BuyandBill.com Pipeline calendar. Comes with Pro. Every aflibercept approval, month by month.
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AHZANTIVE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
67028 Intravitreal injection of a pharmacologic agent (separate procedure) 67028
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

AHZANTIVE Medically Unlikely Edits (MUE)

The most billing units of Q5150 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
4 units / day
= 4 mg per day

MAI 2 · Date of Service Edit: Policy. Absolute per-day limit set by policy or regulation; units above it are not payable, and denials are not appealable on medical-necessity grounds. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

AHZANTIVE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Neovascular (Wet) Age-Related Macular Degeneration (AMD) Macular Edema Following Retinal Vein Occlusion (RVO) Diabetic Macular Edema (DME) Diabetic Retinopathy (DR) Retinopathy of Prematurity (ROP)

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Compare AHZANTIVE with EYLEA and its biosimilars

  • AHZANTIVE Q5150
  • EYLEA J0178
  • PAVBLU Q5147
  • ENZEEVU Q5149
  • OPUVIZ Q5153
  • YESAFILI Q5155

ASP, the Medicare payment limit, WAC and AWP for all 6 drugs on one timeline, with 10+ years of monthly history.

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Frequently Asked Questions

Is there an available AHZANTIVE billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for AHZANTIVE. Please reach out to us if this is a mistake.
Are there any available AHZANTIVE patient assistance programs?
AHZANTIVE patient assistance information can be found through Formycon AG. Visit Here →
Where can I find AHZANTIVE prescribing information?
AHZANTIVE prescribing information can be found at the link below. Visit Here →
Where can I find AHZANTIVE side effect information?
A link for AHZANTIVE side effect information is not available.
Does billing AHZANTIVE require JZ/JW wastage modifiers?
CMS does not include AHZANTIVE (Q5150) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q5150. For more information, visit the link below.

About BuyandBill.com:

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to AHZANTIVE.

J0178EYLEAInjection, aflibercept, 1 mgRegeneron PharmaceuticalsAdded January 1, 2013Q5147PAVBLUInjection, aflibercept-ayyh (pavblu), biosimilar, 1 mgAmgenAdded April 1, 2025Q5149ENZEEVUInjection, aflibercept-abzv (enzeevu), biosimilar, 1 mgSandozAdded April 1, 2025Q5153OPUVIZInjection, aflibercept-yszy (opuviz), biosimilar, 1 mgBiogen Inc.Added July 1, 2025Q5155YESAFILIInjection, aflibercept-jbvf (yesafili), biosimilar, 1 mgBiocon BiologicsAdded October 1, 2025Q5170EydenzeltInjection, aflibercept-boav (eydenzelt), biosimilar, 1 mgAdded July 1, 2026C9151SYFOVREInjection, pegcetacoplan, 1 mgApellis PharmaceuticalsAdded July 1, 2023C9161EYLEA HDInjection, aflibercept hd, 1 mgRegeneron PharmaceuticalsAdded January 1, 2024C9162IZERVAYInjection, avacincaptad pegol, 0.1 mgAstellas PharmaAdded January 1, 2024J0177EYLEA HDInjection, aflibercept hd, 1 mgRegeneron PharmaceuticalsAdded April 1, 2024

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