Xatmep J Code: J8612

Drug & Product Overview

HCPCS Descriptor Methotrexate (xatmep), oral, 2.5 mg

HCPCS Added Date July 1, 2024

Manufacturer Azurity Pharmaceuticals

Route of Administration Oral

Generic Status Single-Source; Branded

Dosage Form Solution

About Xatmep

Xatmep is a medication aligned to the HCPCS J Code: J8612 for billing, pricing, and reimbursement purposes in the United States. Classified under Anti-Anemia, it is administered via the oral route and manufactured by Azurity Pharmaceuticals.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
52652-2001-01	Xatmep	Azurity Pharmaceuticals, Inc.	120	300 MG / 120 ML
52652-2001-06	Xatmep	Azurity Pharmaceuticals, Inc.	60	150 MG / 60 ML

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Xatmep Pricing & Reimbursement

J8612 Private Payer Reimbursement

$23.02 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Methotrexate 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J8610	Generic Code (Multiple Manufacturers)	Methotrexate	Methotrexate; oral, 2.5 mg
J8611	Shorla Oncology	Methotrexate	Methotrexate (jylamvo), oral, 2.5 mg
J8612	Azurity Pharmaceuticals	Methotrexate	Methotrexate (xatmep), oral, 2.5 mg

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

Xatmep Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Lymphoblastic Leukemia Polyarticular Juvenile Idiopathic Arthritis

Drug Class

Folate Analog Metabolic Inhibitor [EPC]Folic Acid Metabolism Inhibitors [MoA]

Frequently Asked Questions

Is there an available Xatmep billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for Xatmep.

Are there any available Xatmep patient assistance programs?

Xatmep patient assistance information can be found through Azurity Pharmaceuticals, Inc.. Visit Here →

Where can I find Xatmep prescribing information?

Xatmep prescribing information can be found at the link below: Visit Here →

Where can I find Xatmep side effect information?

Our team did not identify a source of side effect information for Xatmep.

Does billing Xatmep require JZ/JW wastage modifiers?

CMS does not include Xatmep (J8612) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J8612. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.