Home › Drug Codes › J Codes › J8612 · Xatmep
Updated October 1st, 2026

Xatmep J Code: J8612

Methotrexate (xatmep), oral, 2.5 mg

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Medicare Payment Limit ?
$22.855
down 0.3% since Q3 2026
/ HCPCS billing unitQ3 2026: $22.915
APC Payment Limit ?
$22.855
down 0.3% since Q3 2026
/ HCPCS billing unitQ3 2026: $22.915
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Methotrexate (xatmep), oral, 2.5 mg
HCPCS Added Date July 1, 2024
Manufacturer Azurity Pharmaceuticals
Route of Administration Oral
Generic Status Single-Source; Branded
Dosage Form Solution

About Xatmep

Xatmep is a medication aligned to the HCPCS J Code: J8612 for billing, pricing, and reimbursement purposes in the United States. Classified under Anti-Anemia, it is administered via the oral route and manufactured by Azurity Pharmaceuticals.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
52652-2001-01 Xatmep Azurity Pharmaceuticals, Inc. 120 300 MG / 120 ML
52652-2001-06 Xatmep Azurity Pharmaceuticals, Inc. 60 150 MG / 60 ML
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Xatmep Pricing & Reimbursement

J8612 Private Payer Reimbursement
$23.02 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q4 2026

Methotrexate 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J8610 Generic Code (Multiple Manufacturers) Methotrexate Methotrexate; oral, 2.5 mg
J8611 Shorla Oncology Methotrexate Methotrexate (jylamvo), oral, 2.5 mg
J8612 Azurity Pharmaceuticals Methotrexate Methotrexate (xatmep), oral, 2.5 mg
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

Xatmep Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute Lymphoblastic Leukemia Polyarticular Juvenile Idiopathic Arthritis
Drug Class
Folate Analog Metabolic Inhibitor [EPC]Folic Acid Metabolism Inhibitors [MoA]

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Compare Xatmep with same-ingredient drugs

  • Xatmep J8612
  • METHOTREXATE J8610
  • Jylamvo J8611
  • METHOTREXATE J9260
  • METHOTREXATE J9250

ASP, the Medicare payment limit, WAC and AWP for all 5 drugs on one timeline, with 10+ years of monthly history.

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Frequently Asked Questions

Is there an available Xatmep billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for Xatmep.
Are there any available Xatmep patient assistance programs?
Xatmep patient assistance information can be found through Azurity Pharmaceuticals, Inc.. Visit Here →
Where can I find Xatmep prescribing information?
Xatmep prescribing information can be found at the link below: Visit Here →
Where can I find Xatmep side effect information?
Our team did not identify a source of side effect information for Xatmep.
Does billing Xatmep require JZ/JW wastage modifiers?
CMS does not include Xatmep (J8612) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J8612. For more information, visit the link below.

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