THIOTEPA J Code: J9342

Drug & Product Overview

HCPCS Descriptor Injection, thiotepa, not otherwise specified, 1 mg

HCPCS Added Date July 1, 2025

Manufacturer Multiple Manufacturers

Route of Administration Intracavitary, Intravenous, Intravesical

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Powder, For Solution | Injection, Powder, Lyophilized, For Solution

About THIOTEPA

Thiotepa is a medication aligned to the HCPCS J Code: J9342 for billing, pricing, and reimbursement purposes in the United States. This Oncology medication is administered via the intracavitary, intravenous, or intravesical routes and manufactured by multiple companies.

According to CMS Drug Use Information: Thiotepa is used to treat cancer. It works by slowing or stopping the growth of cancer cells. Some brands may also be given into the bladder to treat bladder cancer or used along with other medications to prevent rejection of a stem cell transplant.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 14 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9292-01	Thiotepa	Hikma Pharmaceuticals USA Inc.	100	100 MG
25021-0246-02	Thiotepa	Sagent Pharmaceuticals	15	15 MG / 1.5 ML
43598-0171-11	Thiotepa	Dr.Reddy's Laboratories Inc.,	100	100 MG
65219-0029-20	Thiotepa	Fresenius Kabi USA, LLC	100	100 MG
70121-1630-01	Tepadina	Amneal Pharmaceuticals LLC	15	15 MG
•••••-••••-•• Log in to view	THIOTEPA
	THIOTEPA
	THIOTEPA

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THIOTEPA Pricing & Reimbursement

J9342 Private Payer Reimbursement

$10.14 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Thiotepa 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J9341	Shorla Oncology	Thiotepa	Injection, thiotepa (tepylute), 1 mg
J9342	Generic Code (Multiple Manufacturers)	Thiotepa	Injection, thiotepa, not otherwise specified, 1 mg

THIOTEPA CPT Administration Codes

CPT Code	Description
96409	Chemotherapy administration; intravenous, push technique, single or initial substance/drug
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Login for More	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure) Login for More

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

THIOTEPA Medically Unlikely Edits (MUE)

The most billing units of J9342 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

60 units / day

= 60 mg per day

Hospital Outpatient

450 units / day

= 450 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

THIOTEPA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Adenocarcinoma of the Breast or Ovary Adenocarcinoma of the breast Adenocarcinoma of the ovary Class 3 Beta-Thalassemia Hodgkin's disease Intracavitary effusions secondary to neoplastic diseases of serosal cavities Lymphosarcoma Malignant Effusions Superficial Papillary Carcinoma of the Urinary Bladder Superficial papillary carcinoma of the urinary bladder

Drug Class

Alkylating Activity [MoA]Alkylating Drug [EPC]

Frequently Asked Questions

Is there an available THIOTEPA billing and coding guide?

Our team has not identified a manufacturer-source of billing and coding information for THIOTEPA. Please reach out to our team if this is a mistake.

Are there any available THIOTEPA patient assistance programs?

Our team has not identified a source of patient assistance information for THIOTEPA. Please reach out to us if this is a mistake.

Where can I find THIOTEPA prescribing information?

THIOTEPA prescribing information can be found at the link below. Visit Here →

Where can I find THIOTEPA side effect information?

Side effect information for THIOTEPA can be found through MedlinePlus. Visit Here →

Does billing THIOTEPA require JZ/JW wastage modifiers?

CMS does not include THIOTEPA (J9342) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9342. For more information, visit the link below.

About BuyandBill.com:

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