Home Drug Codes J Codes J9341 · TEPYLUTE
Updated July 1st, 2026

TEPYLUTE J Code: J9341

Injection, thiotepa (tepylute), 1 mg

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Q4 2026 Medicare Payment Limit for J9341, effective October 1, 2026: $37.841 per HCPCS billing unit, up 3.3% from $36.64. From CMS's final file.

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Medicare Payment Limit ?
$36.64
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, thiotepa (tepylute), 1 mg
HCPCS Added Date July 1, 2025
Manufacturer Shorla Oncology
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose, Multi-Dose
Dosage Form Injection

About TEPYLUTE

Tepylute is a medication aligned to the HCPCS J Code: J9341 for billing, pricing, and reimbursement purposes in the United States. Classified under Oncology, it is administered via the intravenous route and manufactured by Shorla Oncology.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
81927-0105-01 Tepylute Shorla Oncology Inc. 15 15 MG / 1.5 ML
81927-0106-01 Tepylute Shorla Oncology Inc. 100 100 MG / 10 ML
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TEPYLUTE Pricing & Reimbursement

J9341 Private Payer Reimbursement
$39.50 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Thiotepa 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J9341 Shorla Oncology Thiotepa Injection, thiotepa (tepylute), 1 mg
J9342 Generic Code (Multiple Manufacturers) Thiotepa Injection, thiotepa, not otherwise specified, 1 mg

TEPYLUTE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415 Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

TEPYLUTE Medically Unlikely Edits (MUE)

The most billing units of J9341 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
60 units / day
= 60 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

TEPYLUTE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Adenocarcinoma of the Breast or Ovary
Drug Class
Alkylating Activity [MoA]Alkylating Drug [EPC]

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Frequently Asked Questions

Is there an available TEPYLUTE billing and coding guide?
Billing and coding information for TEPYLUTE can be found through Shorla Oncology. Visit Here →
Are there any available TEPYLUTE patient assistance programs?
TEPYLUTE patient assistance information can be found through Shorla Oncology. Visit Here →
Where can I find TEPYLUTE prescribing information?
TEPYLUTE prescribing information can be found at the link below. Visit Here →
Where can I find TEPYLUTE side effect information?
Side effect information for TEPYLUTE can be found through MedlinePlus. Visit Here →
Does billing TEPYLUTE require JZ/JW wastage modifiers?
CMS does not include TEPYLUTE (J9341) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9341. For more information, visit the link below.

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