CPT Administration Code: 96409 | Chemotherapy Administration

Code Overview

CPT® administration code details for 96409.

CPT Code Descriptor Chemotherapy administration; intravenous, push technique, single or initial substance/drug

Code Category Chemotherapy Administration

Route / Technique Intravenous Push

Code Type Initial / Primary Code

About Chemotherapy Administration – 96409

CPT 96409 describes the intravenous push administration of a single chemotherapy or other highly complex drug or biologic agent. It is reported as the initial service when a physician or qualified clinical staff administers the agent by rapid IV push, meaning the individual physically injects the substance or an infusion running less than 15 minutes is provided. This code is used once per encounter to capture the first or only push agent given, distinct from any subsequent pushes of additional different drugs.

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96409 RVU Breakdown & Medicare Reimbursement

Based on the CY 2026 CMS Physician Fee Schedule. National payment amounts, before geographic (GPCI) adjustment.

Component	Facility	Non-Facility
Work RVU — physician work	0.24	0.24
Practice Expense RVU — staff, supplies, equipment	2.83	2.83
Malpractice RVU — professional liability	0.06	0.06
Total RVUs	3.13	3.13
Medicare Payment — Total RVUs × $33.4009 CF	$104.54	$104.54

CY 2026 Medicare Conversion Factor: $33.4009. Facility and non-facility practice-expense RVUs are equal for this code.

96409 Locality-Adjusted Rates

Medicare payment varies by locality via GPCI adjustment. Log in to view rates for all 100+ Medicare localities.

Medicare Locality	Facility	Non-Facility
National (unadjusted)	$104.54	$104.54
Los Angeles–Long Beach, CA
Manhattan, NY
Houston, TX
Miami, FL

Related Administration Codes

The chemotherapy IV-push code family. Report one initial code per encounter; add-on codes are listed separately in addition to the primary procedure.

CPT Code	Description	Type
96409This page	Chemotherapy administration; intravenous, push technique, single or initial substance/drug	Initial
96411	Chemotherapy administration; intravenous, push technique, each additional substance/drug (List separately in addition to code for primary procedure)	Add-on

Drugs Commonly Billed with 96409

HCPCS-coded drugs frequently administered under this CPT code. The list below is not exhaustive.

HCPCS Code	Drug	HCPCS Descriptor
J8600	ALKERAN	Melphalan; oral, 2 mg
J9046	Bortezomib	Injection, bortezomib (dr. reddy's), not therapeutically equivalent to j9041, 0.1 mg
J9051	BORTEZOMIB (MAIA)	Injection, bortezomib (maia), not therapeutically equivalent to j9041, 0.1 mg
J9074	Cyclophosphamide (Sandoz)	Injection, cyclophosphamide (sandoz), 5 mg
J8560	ETOPOSIDE	Etoposide; oral, 50 mg

Frequently Asked Questions

What are CPT Administration Codes?

CPT administration codes cover the work of giving a drug to a patient, such as an injection or an infusion. The drug itself is billed with its HCPCS J-code, and the administration is billed with a CPT code. Both go on the same claim. Learn More →

What is the Medicare Conversion Factor?

The conversion factor is the dollar amount CMS uses to turn a code's total RVUs into a Medicare payment. This page uses the CY 2026 conversion factor of $33.4009. CMS updates it every year in the Physician Fee Schedule final rule.

Facility vs. Non-Facility?

The non-facility rate applies in a physician office, where the practice pays for its own staff, supplies, and equipment, so the rate is usually higher. The facility rate applies in hospital outpatient departments and ASCs, where the facility bills for those costs separately.

How do I decide which administration code to use?

Pick the code that matches the type of drug, the route, and how long the administration takes. Start from the highest-ranking service you performed, then add the appropriate add-on codes for extra time or extra drugs. Manufacturer billing and coding guides often list suggested administration codes.

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CPT Administration Code: 96409 – Chemotherapy Administration