Home Drug Codes J Codes J1410 · PREMARIN
Updated July 1st, 2026

PREMARIN J Code: J1410

Injection, estrogen conjugated, per 25 mg

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Q4 2026 Medicare Payment Limit for J1410, effective October 1, 2026: $402.131 per HCPCS billing unit, up 0.2% from $401.503. From CMS's final file.

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Medicare Payment Limit ?
$401.503
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$401.503
/ HCPCS billing unit · APC 9038
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, estrogen conjugated, per 25 mg
HCPCS Added Date January 1, 1982
Manufacturer Pfizer
Route of Administration Intramuscular, Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection, Powder, Lyophilized, For Solution

About PREMARIN

Premarin is a medication aligned to the HCPCS J Code: J1410 for billing, pricing, and reimbursement purposes in the United States. This Hormone Replacement medication is administered via the intramuscular or intravenous routes and manufactured by Pfizer.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00046-0749-05 Premarin Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. 1 25 MG / 5 ML
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PREMARIN Pricing & Reimbursement

J1410 Private Payer Reimbursement
$391.65 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

PREMARIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96372 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular Login for More
Not on the CMS JW / JZ list

CMS does not include Premarin (J1410) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1410. Wastage billing guide →

PREMARIN Medically Unlikely Edits (MUE)

The most billing units of J1410 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 25 mg.

Practitioner Office & Hospital Outpatient
4 units / day
= 100 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

PREMARIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology
Drug Class
Estrogen Receptor Agonists [MoA]Estrogen [EPC]EstrogensConjugated (USP) [CS]

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Frequently Asked Questions

Is there an available Premarin billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for PREMARIN.
Are there any available Premarin patient assistance programs?
PREMARIN patient assistance information can be found through Pfizer. Visit Here →
Where can I find Premarin prescribing information?
PREMARIN prescribing information can be found at the link below: Visit Here →
Where can I find Premarin side effect information?
Information regarding PREMARIN's side effects can be found at MedlinePlus Visit Here →
Does billing PREMARIN require JZ/JW wastage modifiers?
CMS does not include PREMARIN (J1410) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1410. For more information, visit the link below.

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