Home Drug Codes J Codes J1380 · DELESTROGEN
Updated July 1st, 2026

DELESTROGEN J Code: J1380

Injection, estradiol valerate, up to 10 mg

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Q4 2026 Medicare Payment Limit for J1380, effective October 1, 2026: $7.693 per HCPCS billing unit, down 0.1% from $7.702. From CMS's final file.

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Medicare Payment Limit ?
$7.702
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
10
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Drug & Product Overview

HCPCS Descriptor Injection, estradiol valerate, up to 10 mg
HCPCS Added Date January 1, 1982
Manufacturer Multiple Manufacturers
Route of Administration Intramuscular
Generic Status Multi-Source; Generic
Dosage Type Multi-Dose
Dosage Form Injection | Injection, Solution

About DELESTROGEN

Delestrogen is a medication aligned to the HCPCS J Code: J1380 for billing, pricing, and reimbursement purposes in the United States. This Hormone Replacement medication is administered via the intramuscular route and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is a hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure) and by men to treat prostate cancer.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 10 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00143-9289-01 Estradiol Valerate Hikma Pharmaceuticals USA Inc. 5 50 MG / 5 ML
00143-9291-01 Estradiol Valerate Hikma Pharmaceuticals USA Inc. 20 200 MG / 5 ML
00517-0420-01 Estradiol Valerate American Regent, Inc. 10 100 MG / 5 ML
42023-0110-01 Delestrogen Par Health USA, LLC 5 50 MG / 5 ML
70700-0273-22 Estradiol valerate Xiromed, LLC 5 50 MG / 5 ML
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DELESTROGEN Pricing & Reimbursement

J1380 Private Payer Reimbursement
$7.36 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

DELESTROGEN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96372 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular
Not on the CMS JW / JZ list

CMS does not include Delestrogen (J1380) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1380. Wastage billing guide →

DELESTROGEN Medically Unlikely Edits (MUE)

The most billing units of J1380 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg.

Practitioner Office & Hospital Outpatient
4 units / day
= 40 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

DELESTROGEN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Advanced androgen-dependent carcinoma of the prostate Hypoestrogenism due to hypogonadism, castration or primary ovarian failure Moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause Moderate to severe vasomotor symptoms associated with the menopause advanced androgen-dependent carcinoma of the prostate hypoestrogenism due to hypogonadism, castration, or primary ovarian failure moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause moderate to severe vasomotor symptoms associated with the menopause
Drug Class
Estradiol Congeners [CS]Estrogen Receptor Agonists [MoA]Estrogen [EPC]

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Frequently Asked Questions

Is there an available Delestrogen billing and coding guide?
We have not yet identified a manufacturer source of Delestrogen billing and coding information.
Are there any available Delestrogen patient assistance programs?
Our team did not identify a source for Delestrogen patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Delestrogen prescribing information?
DELESTROGEN prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Delestrogen side effect information?
Our team has not yet identified a source of side effects information for DELESTROGEN. Please check back in a few weeks.
Does billing DELESTROGEN require JZ/JW wastage modifiers?
CMS does not include DELESTROGEN (J1380) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1380. For more information, visit the link below.

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