DELESTROGEN J Code: J1380
Injection, estradiol valerate, up to 10 mg
Q4 2026 Medicare Payment Limit for J1380, effective October 1, 2026: $7.693 per HCPCS billing unit, down 0.1% from $7.702. From CMS's final file.
Drug & Product Overview
About DELESTROGEN
Delestrogen is a medication aligned to the HCPCS J Code: J1380 for billing, pricing, and reimbursement purposes in the United States. This Hormone Replacement medication is administered via the intramuscular route and manufactured by multiple companies.
According to CMS Drug Use Information: This medication is a hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure) and by men to treat prostate cancer.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 5 of 10 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 00143-9289-01 | Estradiol Valerate | Hikma Pharmaceuticals USA Inc. | 5 | 50 MG / 5 ML |
| 00143-9291-01 | Estradiol Valerate | Hikma Pharmaceuticals USA Inc. | 20 | 200 MG / 5 ML |
| 00517-0420-01 | Estradiol Valerate | American Regent, Inc. | 10 | 100 MG / 5 ML |
| 42023-0110-01 | Delestrogen | Par Health USA, LLC | 5 | 50 MG / 5 ML |
| 70700-0273-22 | Estradiol valerate | Xiromed, LLC | 5 | 50 MG / 5 ML |
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DELESTROGEN Pricing & Reimbursement
National median reimbursement across major commercial payers.
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Login to use the calculator →DELESTROGEN CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular |
CMS does not include Delestrogen (J1380) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1380. Wastage billing guide →
DELESTROGEN Medically Unlikely Edits (MUE)
The most billing units of J1380 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
DELESTROGEN Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
Is there an available Delestrogen billing and coding guide?
Are there any available Delestrogen patient assistance programs?
Where can I find Delestrogen prescribing information?
Where can I find Delestrogen side effect information?
Does billing DELESTROGEN require JZ/JW wastage modifiers?
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