PHOTREXA CROSS-LINKING J Code: J2787

Drug & Product Overview

HCPCS Descriptor Riboflavin 5'-phosphate, ophthalmic solution (photrexa viscous/photrexa), up to 3 ml

HCPCS Added Date January 1, 2019

Manufacturer Glaukos

Route of Administration Ophthalmic

Generic Status Single-Source; Branded

Dosage Form Kit

About PHOTREXA CROSS-LINKING

Photrexa Cross-linking is a medication aligned to the HCPCS J Code: J2787 for billing, pricing, and reimbursement purposes in the United States. This Ophthalmology medication is administered via the ophthalmic route and manufactured by Glaukos.

Manufacturers, reach out to us to add more information.

NDC Code Information

2 NDC packages are crosswalked to J2787. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	PHOTREXA CROSS-LINKING
	PHOTREXA CROSS-LINKING

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PHOTREXA CROSS-LINKING Pricing & Reimbursement

J2787 Private Payer Reimbursement

$2,300.30 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Riboflavin 5-phosphate Ophthalmic 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J2787	Glaukos	Riboflavin 5-phosphate Ophthalmic	Riboflavin 5'-phosphate, ophthalmic solution (photrexa viscous/photrexa), up to 3 ml
J2789	Glaukos	Riboflavin 5-phosphate Ophthalmic	Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml

PHOTREXA CROSS-LINKING Medically Unlikely Edits (MUE)

The most billing units of J2787 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 3 ml.

Practitioner Office & Hospital Outpatient

2 units / day

= 6 ml per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Not on the CMS JW / JZ list

CMS does not include Photrexa Cross-linking (J2787) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2787. Wastage billing guide →

PHOTREXA CROSS-LINKING Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Corneal Ectasia Following Refractive Surgery Progressive Keratoconus

Frequently Asked Questions

Is there an available Photrexa Cross-Linking billing and coding guide?

Billing and coding information for PHOTREXA CROSS-LINKING can be found through Glaukos. Visit Here →

Are there any available Photrexa Cross-Linking patient assistance programs?

PHOTREXA CROSS-LINKING patient assistance information can be found through Glaukos. Visit Here →

Where can I find Photrexa Cross-Linking prescribing information?

PHOTREXA CROSS-LINKING prescribing information can be found at the link below: Visit Here →

Where can I find Photrexa Cross-Linking side effect information?

Our team has not yet identified a source of side effects information for PHOTREXA CROSS-LINKING. Please check back in a few weeks.

Does billing PHOTREXA CROSS-LINKING require JZ/JW wastage modifiers?

CMS does not include PHOTREXA CROSS-LINKING (J2787) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2787. For more information, visit the link below.

About BuyandBill.com:

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