Home › Drug Codes › J Codes › J2789 · Epioxa HD/Epioxa
Updated October 1st, 2026

Epioxa HD/Epioxa J Code: J2789

Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml

Medicare Payment Limit ?
$41,359.618
/ HCPCS billing unit
APC Payment Limit ?
$41,359.618
/ HCPCS billing unit · APC 0941
ASP ?
$39,018.508
/ HCPCS billing unit
WAC ?
$39,250.00
/ HCPCS billing unit
AWP ?
$47,100.00
/ HCPCS billing unit
NDCs Crosswalked ?
1
View NDC crosswalk →

Drug & Product Overview

HCPCS Descriptor Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml
HCPCS Added Date July 1, 2026
Manufacturer Glaukos
Route of Administration Ophthalmic
Generic Status Single-Source; Branded
Dosage Form Kit

About Epioxa HD/Epioxa

Epioxa Hd/epioxa is a medication aligned to the HCPCS J Code: J2789 for billing, pricing, and reimbursement purposes in the United States. Classified under Ophthalmology, it is administered via the ophthalmic route and manufactured by Glaukos.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Package Manufacturer HCPCS Units WAC AWP
25357-0024-01
Kit Epioxa Cross-Linking Ophthalmic Kit - 1 KIT in 1 CARTON (25357-024-01) * 1 SYRINGE, GLASS in 1 POUCH (25357-026-01) / 2 mL in 1 SYRINGE, GLASS * 1 SYRINGE, GLASS in 1 POUCH (25357-027-01) / 2 mL in 1 SYRINGE, GLASS
Glaukos Corporation 2 $78,500.00 $39,250.00 / unit $94,200.00 $47,100.00 / unit

Effective 1/16/26 (WAC & AWP)

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Epioxa HD/Epioxa Pricing & Reimbursement

Historical Graphing and Billing Calculator

HCPCS Units
%
Common:

Estimates only. Payer reimbursement varies by contract, site of care, and sequestration.

Estimated Reimbursement

Riboflavin 5-phosphate Ophthalmic 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J2787 Glaukos Riboflavin 5-phosphate Ophthalmic Riboflavin 5'-phosphate, ophthalmic solution (photrexa viscous/photrexa), up to 3 ml
J2789 Glaukos Riboflavin 5-phosphate Ophthalmic Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

Epioxa HD/Epioxa Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Keratoconus (Epithelium-On Corneal Collagen Cross-Linking)
Drug Class
Ophthalmic photoenhancers

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Frequently Asked Questions

Is there an available Epioxa HD/Epioxa billing and coding guide?
Billing and coding information for Epioxa HD/Epioxa can be found through Glaukos. Visit Here →
Are there any available Epioxa Hd/Epioxa patient assistance programs?
EPIOXA HD/EPIOXA patient assistance information can be found through GLAUKOS. Visit Here →
Where can I find Epioxa Hd/Epioxa prescribing information?
EPIOXA HD/EPIOXA prescribing information can be found at the link below: Visit Here →
Where can I find Epioxa Hd/Epioxa side effect information?
Information regarding EPIOXA HD/EPIOXA's side effects can be found at MedlinePlus Visit Here →
Does billing EPIOXA HD/EPIOXA require JZ/JW wastage modifiers?
This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers.

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