Home Drug Codes J Codes J1643 · HEPARIN SODIUM
Updated July 1st, 2026

HEPARIN SODIUM J Code: J1643

Injection, heparin sodium (pfizer), not therapeutically equivalent to j1644, per 1000 units

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Q4 2026 Medicare Payment Limit for J1643, effective October 1, 2026: $2.248 per HCPCS billing unit, up 31.4% from $1.711. From CMS's final file.

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Medicare Payment Limit ?
$1.711
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Injection, heparin sodium (pfizer), not therapeutically equivalent to j1644, per 1000 units
HCPCS Added Date January 1, 2023
Manufacturer Pfizer
Route of Administration Intravenous, Subcutaneous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection

About HEPARIN SODIUM

Heparin Sodium is a medication aligned to the HCPCS J Code: J1643 for billing, pricing, and reimbursement purposes in the United States. Classified under Hematology, it is administered via the intravenous or subcutaneous routes and manufactured by Pfizer.

According to CMS Drug Use Information: This medication is used to prevent and treat blood clots. It may be used to prevent and treat blood clots in the lungs/legs (including in patients with atrial fibrillation). It may be used to treat certain blood clotting disorders. It may also be used to prevent blood clots after surgery, during dialysis, during blood transfusions, when collecting blood samples, or when a person is unable to move for a long time. Heparin helps to keep blood flowing smoothly by making a certain natural substance in your body (anti-clotting protein) work better. It is known as an anticoagulant.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 1 of 2 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00069-0043-01 Heparin Sodium Pfizer Laboratories Div Pfizer Inc 50 Heparin Sodium Intrave nous Injection 2… Login for More
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HEPARIN SODIUM Pricing & Reimbursement

J1643 Private Payer Reimbursement
$2.32 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Heparin Sodium 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J1642 Generic Code (Multiple Manufacturers) Heparin Sodium Injection, heparin sodium, (heparin lock flush), per 10 units
J1643 Pfizer Heparin Sodium Injection, heparin sodium (pfizer), not therapeutically equivalent to j1644, per 1000 units
J1644 Generic Code (Multiple Manufacturers) Heparin Sodium Injection, heparin sodium, per 1000 units

HEPARIN SODIUM CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
96372 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular Login for More
96374 Login for More Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug Login for More
Not on the CMS JW / JZ list

CMS does not include Heparin Sodium (J1643) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1643. Wastage billing guide →

HEPARIN SODIUM Medically Unlikely Edits (MUE)

The most billing units of J1643 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1000 units.

Practitioner Office & Hospital Outpatient
40 units / day
= 40,000 units per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

units Enter a dose to see how many billing units it is and whether it is under the limit.

HEPARIN SODIUM Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Acute and chronic consumption coagulopathies (disseminated intravascular coagulation) Anticoagulation in blood transfusions, extracorporeal circulation, and dialysis procedures Peripheral arterial embolism Prevention of clotting in arterial and cardiac surgery Prophylaxis of postoperative thromboembolism Thromboembolic complications associated with atrial fibrillation Venous thrombosis and pulmonary embolism
Drug Class
Anti-coagulant [EPC]Heparin [CS]Unfractionated Heparin [EPC]

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Frequently Asked Questions

Is there an available Heparin Sodium billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for HEPARIN SODIUM.
Are there any available Heparin Sodium patient assistance programs?
HEPARIN SODIUM patient assistance information can be found through Pfizer. Visit Here →
Where can I find Heparin Sodium prescribing information?
HEPARIN SODIUM prescribing information can be found at the link below: Visit Here →
Where can I find Heparin Sodium side effect information?
Our team has not yet identified a source of side effects information for HEPARIN SODIUM. Please check back in a few weeks.
Does billing HEPARIN SODIUM require JZ/JW wastage modifiers?
CMS does not include HEPARIN SODIUM (J1643) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J1643. For more information, visit the link below.

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