FASENRA J Code: J0517

Drug & Product Overview

HCPCS Descriptor Injection, benralizumab, 1 mg

HCPCS Added Date January 1, 2019

Manufacturer Astrazeneca

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Solution

About FASENRA

Fasenra is a medication aligned to the HCPCS J Code: J0517 for billing, pricing, and reimbursement purposes in the United States. It is an Anti-Eosinophil Asthma drug administered via the subcutaneous route and manufactured by Astrazeneca.

According to CMS Drug Use Information: Benralizumab is used along with other medications to control and prevent symptoms (such as wheezing and shortness of breath) caused by asthma. Controlling symptoms of asthma helps you maintain your normal activities and decreases time lost from work or school. Benralizumab is also used to treat certain immune system disorders (eosinophilic granulomatosis with polyangiitis - EGPA, hypereosinophilic syndrome). This medication works by decreasing a certain type of white blood cell (eosinophils). This effect helps reduce swelling (inflammation) of the airways and other parts of the body. This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler as prescribed.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00310-1730-30	Fasenra	AstraZeneca Pharmaceuticals LP	30	30 MG / 1 ML
00310-1745-01	Fasenra	AstraZeneca Pharmaceuticals LP	10	10 MG / 0.5 ML
00310-1830-30	Fasenra	AstraZeneca Pharmaceuticals LP	30	30 MG / 1 ML

Login for the full NDC crosswalk View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

FASENRA Pricing & Reimbursement

J0517 Private Payer Reimbursement

$165.01 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

FASENRA CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

JW / JZ modifiers apply

CMS has identified Fasenra (J0517) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

FASENRA Medically Unlikely Edits (MUE)

The most billing units of J0517 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

30 units / day

= 30 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

FASENRA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Asthma Eosinophilic Granulomatosis with Polyangiitis Hypereosinophilic Syndrome

Drug Class

Interleukin 5 Receptor alpha-directed Antibody Interactions [MoA]Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC]

Frequently Asked Questions

Is there an available Fasenra billing and coding guide?

Billing and coding information for FASENRA can be found through Astrazeneca. Visit Here →

Are there any available Fasenra patient assistance programs?

FASENRA patient assistance information can be found through Astrazeneca. Visit Here →

Where can I find Fasenra prescribing information?

FASENRA prescribing information can be found at the link below: Visit Here →

Where can I find Fasenra side effect information?

Information regarding FASENRA's side effects can be found at MedlinePlus Visit Here →

Does billing FASENRA require JZ/JW wastage modifiers?

CMS has identified FASENRA(J0517) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.