DDAVP J Code: J2597
Injection, desmopressin acetate, per 1 mcg
Q4 2026 Medicare Payment Limit for J2597, effective October 1, 2026: $3.475 per HCPCS billing unit, down 2.4% from $3.562. From CMS's final file.
Drug & Product Overview
About DDAVP
Ddavp is a medication aligned to the HCPCS J Code: J2597 for billing, pricing, and reimbursement purposes in the United States. Classified under Hormone Replacement, it is administered via the intravenous or subcutaneous routes and manufactured by multiple companies.
According to CMS Drug Use Information: Desmopressin is used to control the amount of urine your kidneys make. Normally, the amount of urine you make is controlled by a certain substance in the body called vasopressin. In people who have "water diabetes" (diabetes insipidus) or certain kinds of head injury or brain surgery, the body does not make enough vasopressin. Desmopressin is a man-made form of vasopressin and is used to replace a low level of vasopressin. This medication helps to control increased thirst and too much urination due to these conditions, and helps prevent dehydration. Desmopressin is also used to control bleeding caused by surgery or injuries in people with certain bleeding problems (hemophilia A, type 1 von Willebrand's disease). It works by helping the body with normal blood clotting.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. Showing 5 of 28 NDCs — log in for the full crosswalk.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 25021-0460-01 | desmopressin acetate | Sagent Pharmaceuticals | 40 | 4 MCG / 1 ML |
| 39822-6200-02 | Desmopressin Acetate | XGen Pharmaceuticals DJB, Inc. | 40 | 4 MCG / 1 ML |
| 43598-0053-11 | Desmopressin Acetate | Dr. Reddy's Laboratories Inc. | 40 | 40 MCG / 10 ML |
| 43598-0931-09 | Desmopressin Acetate | Dr.Reddys' Laboratories Inc | 40 | 4 MCG / 1 ML |
| 55566-2200-00 | Ddavp | Ferring Pharmaceuticals Inc. | 40 | 4 MCG / 1 ML |
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DDAVP Pricing & Reimbursement
National median reimbursement across major commercial payers.
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Login to use the calculator →DDAVP CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular |
| 96374 | Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug |
CMS does not include Ddavp (J2597) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2597. Wastage billing guide →
DDAVP Medically Unlikely Edits (MUE)
The most billing units of J2597 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mcg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
DDAVP Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
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