Home › Drug Codes › J Codes › J7192 · ADVATE
Updated July 1st, 2026

ADVATE J Code: J7192

Factor viii (antihemophilic factor, recombinant) per i.u., not otherwise specified

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Q4 2026 Medicare Payment Limit for J7192, effective October 1, 2026: $1.616 per HCPCS billing unit, up 2.3% from $1.58. From CMS's final file.

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Medicare Payment Limit ?
$1.58
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
$1.58
/ HCPCS billing unit · APC 0927
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
17
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Drug & Product Overview

HCPCS Descriptor Factor viii (antihemophilic factor, recombinant) per i.u., not otherwise specified
HCPCS Added Date January 1, 1994
Manufacturer Multiple Manufacturers
Route of Administration Multiple Routes, Intravenous
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Kit

About ADVATE

Advate is a medication aligned to the HCPCS J Code: J7192 for billing, pricing, and reimbursement purposes in the United States. It is a Hematology drug administered via the multiple routes or intravenous routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used to control and prevent bleeding episodes in people with low levels of factor VIII (hemophilia A). It is also used in these patients before surgery to prevent bleeding. People with low factor VIII levels are at risk for bleeding longer after an injury/surgery and for bleeding inside the body (especially into the joints and muscles). This product contains a man-made form of factor VIII, also called antihemophilic factor. This product is used to temporarily replace the missing factor VIII, a protein (clotting factor) that is normally in the blood, so that the blood can clot and the bleeding can stop. This medication should not be used to treat von Willebrand disease.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 17 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00944-2841-10 Recombinate Takeda Pharmaceuticals America, Inc. 1 Kit
00944-2842-10 Recombinate Takeda Pharmaceuticals America, Inc. 1 Kit
00944-2843-10 Recombinate Takeda Pharmaceuticals America, Inc. 1 Kit
00944-2844-10 Recombinate Takeda Pharmaceuticals America, Inc. 1 Kit
00944-2845-10 Recombinate Takeda Pharmaceuticals America, Inc. 1 Kit
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ADVATE Pricing & Reimbursement

J7192 Private Payer Reimbursement
$1.45 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

ADVATE CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

CMS does not include Advate (J7192) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7192. Wastage billing guide →

ADVATE Medically Unlikely Edits (MUE)

The most billing units of J7192 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 iu.

Practitioner Office & Hospital Outpatient
22,000 units / day
= 22,000 iu per day

MAI 1 · Line Edit. Per-line limit: units are checked per claim line; medically necessary units beyond the limit may be billable on separate lines with appropriate modifiers. See all MUE limits →

iu Enter a dose to see how many billing units it is and whether it is under the limit.

ADVATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Hemophilia A Hemophilia A (congenital factor VIII deficiency) Hemophilia A with Factor VIII inhibitors

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Frequently Asked Questions

Is there an available Advate billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for ADVATE.
Are there any available Advate patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for ADVATE.
Where can I find Advate prescribing information?
Our team is still working to identify a prescribing information source for ADVATE
Where can I find Advate side effect information?
Our team has not yet identified a source of side effects information for ADVATE. Please check back in a few weeks.
Does billing ADVATE require JZ/JW wastage modifiers?
CMS does not include ADVATE (J7192) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7192. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to ADVATE.

J7185XYNTHAInjection, factor viii (antihemophilic factor, recombinant) (xyntha), per i.u.PfizerAdded January 1, 2010J7209NUWIQInjection, factor viii, (antihemophilic factor, recombinant), (nuwiq), 1 i.u.OctapharmaAdded January 1, 2017J7211KOVALTRYInjection, factor viii, (antihemophilic factor, recombinant), (kovaltry), 1 i.u.Bayer PharmaceuticalAdded January 1, 2018J7172HYMPAVZIInjection, marstacimab-hncq, 0.5 mgPfizerAdded July 1, 2025J7182NOVOEIGHTInjection, factor viii, (antihemophilic factor, recombinant), (novoeight), per iuNovo NordiskAdded January 1, 2015J7187HUMATE-PInjection, von willebrand factor complex (humate-p), per iu vwf:rcoCSL BehringAdded January 1, 2007J7190ALPHANATEFactor viii (antihemophilic factor, human) per i.u.Multiple ManufacturersAdded January 1, 1986J7204ESPEROCTInjection, factor viii, antihemophilic factor (recombinant), (esperoct), glycopegylated-exei, per iuNovo NordiskAdded July 1, 2020J7205ELOCTATEInjection, factor viii fc fusion protein (recombinant), per iuBioverativ TherapeuticsAdded January 1, 2016J7207ADYNOVATEInjection, factor viii, (antihemophilic factor, recombinant), pegylated, 1 i.u.Takeda PharmaceuticalsAdded January 1, 2017