Daptomycin J Code: J0877
Injection, daptomycin (hospira), not therapeutically equivalent to j0878, 1 mg
Q4 2026 Medicare Payment Limit for J0877, effective October 1, 2026: $0.022 per HCPCS billing unit, down 61.4% from $0.057. From CMS's final file.
Drug & Product Overview
About Daptomycin
Daptomycin is a medication aligned to the HCPCS J Code: J0877 for billing, pricing, and reimbursement purposes in the United States. It is an Antibiotic drug administered via the intravenous route and manufactured by multiple companies.
According to CMS Drug Use Information: This medication is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria. Daptomycin is not recommended for use in children younger than 12 months due to possible risk of serious side effects.
Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.
NDC Code Information
Based on publicly available CMS files. The list of NDCs below is not exhaustive.
| NDC Code | Drug | Manufacturer | Billing Units / Pkg | Package Size |
|---|---|---|---|---|
| 00143-9445-01 | Daptomycin | Hikma Pharmaceuticals USA Inc. | 500 | 500 MG / 10 ML |
| 00409-0120-01 | Daptomycin | Hospira, Inc. | 350 | 350 MG / 7 ML |
| 00409-0122-01 | Daptomycin | Hospira, Inc. | 500 | 500 MG / 10 ML |
| 72572-0158-01 | Daptomycin | Civica, Inc. | 500 | 500 MG / 10 ML |
Daptomycin Pricing & Reimbursement
National median reimbursement across major commercial payers.
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Login to use the calculator →Daptomycin 505(b)(2) Information:
| HCPCS Code | Manufacturer | Active Ingredient | HCPCS Description |
|---|---|---|---|
| J0871 | Par Pharmaceutical, Inc | Daptomycin | Injection, daptomycin (endo), not therapeutically equivalent to j0878, 1 mg |
| J0872 | Generic Code (Multiple Manufacturers) | Daptomycin | Injection, daptomycin (xellia), unrefrigerated, not therapeutically equivalent to j0878 or j0873, 1 mg |
| J0873 | Generic Code (Multiple Manufacturers) | Daptomycin | Injection, daptomycin (xellia), not therapeutically equivalent to j0878 or j0872, 1 mg |
| J0874 | Baxter Healthcare | Daptomycin | Injection, daptomycin (baxter), not therapeutically equivalent to j0878, 1 mg |
| J0877 | Generic Code (Multiple Manufacturers) | Daptomycin | Injection, daptomycin (hospira), not therapeutically equivalent to j0878, 1 mg |
| J0878 Log in to view | Generic Code (Multiple Manufacturers) Log in to view | Daptomycin Log in to view | Injection, daptomycin, 1 mg Log in to view |
Daptomycin CPT Administration Codes
The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.
| CPT Code | Description |
|---|---|
| 96365 | Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour |
| 96366 | Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure) |
CMS has identified Daptomycin (J0877) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →
Daptomycin Medically Unlikely Edits (MUE)
The most billing units of J0877 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.
MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →
Daptomycin Clinical Information
Indications and drug classification.
This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.
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Frequently Asked Questions
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