CROFAB J Code: J0840

Drug & Product Overview

HCPCS Descriptor Injection, crotalidae polyvalent immune fab (ovine), up to 1 gram

HCPCS Added Date January 1, 2012

Manufacturer BTG International

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Form Injection, Powder, Lyophilized, For Solution

About CROFAB

Crofab is a medication aligned to the HCPCS J Code: J0840 for billing, pricing, and reimbursement purposes in the United States. This Immunology medication is administered via the intravenous route and manufactured by BTG International.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
50633-0110-12	CroFab	BTG International Inc.	2	CroFab Intravenous Inj ection 1 G/1 - 2… Login for More

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CROFAB Pricing & Reimbursement

J0840 Private Payer Reimbursement

$1,836.08 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

CROFAB CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Crofab (J0840) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

CROFAB Medically Unlikely Edits (MUE)

The most billing units of J0840 Medicare will pay for one patient in one day, as published by CMS. 1 unit = up to 1 gm. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

6 units / day

Physician office · clinic

Hospital Outpatient

18 units / day

Outpatient hospital · OPPS

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

CROFAB Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

North American pit viper envenomation

Drug Class

Antivenin [EPC]Antivenins [Chemical/Ingredient]Passively Acquired Immunity [PE]Venom Neutralization [MoA]

Frequently Asked Questions

Is there an available Crofab billing and coding guide?

Billing and coding information for CROFAB can be found through BTG International. Visit Here →

Are there any available Crofab patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for CROFAB.

Where can I find Crofab prescribing information?

CROFAB prescribing information can be found at the link below: Visit Here →

Where can I find Crofab side effect information?

Our team has not yet identified a source of side effects information for CROFAB. Please check back in a few weeks.

Does billing CROFAB require JZ/JW wastage modifiers?

CMS has identified CROFAB(J0840) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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