COMBOGESIC J Code: J0138

Drug & Product Overview

HCPCS Descriptor Injection, acetaminophen 10 mg and ibuprofen 3 mg

HCPCS Added Date October 1, 2024

Manufacturer Hikma

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection

About COMBOGESIC

Combogesic is a medication aligned to the HCPCS J Code: J0138 for billing, pricing, and reimbursement purposes in the United States. This Non-Opioid Analgesic medication is administered via the intravenous route and manufactured by Hikma.

According to CMS Drug Use Information: This medication contains 2 ingredients: ibuprofen and acetaminophen. It is used to relieve mild to moderate pain. When used with an opioid (such as morphine), it may be used to relieve moderate to severe pain. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). This combination product works by blocking your body's production of certain natural substances that cause inflammation. This effect helps to decrease swelling and pain.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 1 of 2 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9150-10	Combogesic Iv	Hikma Pharmaceuticals USA Inc.	1000	1000 MG / 100 ML
•••••-••••-•• Log in to view	COMBOGESIC

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COMBOGESIC Pricing & Reimbursement

J0138 Private Payer Reimbursement

$0.13 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

Acetaminophen And Ibuprofen Injection 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J0138	Hikma	Acetaminophen And Ibuprofen Injection	Injection, acetaminophen 10 mg and ibuprofen 3 mg

COMBOGESIC CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

COMBOGESIC Medically Unlikely Edits (MUE)

The most billing units of J0138 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 10 mg/3mg.

Practitioner Office & Hospital Outpatient

400 units / day

= 4,000 mg/3mg per day

MAI 2 · Date of Service Edit: Policy. Absolute per-day limit set by policy or regulation; units above it are not payable, and denials are not appealable on medical-necessity grounds. See all MUE limits →

COMBOGESIC Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Short-term management of mild to moderate acute pain (adults)

Drug Class

Anti-Inflammatory AgentsNon-Steroidal [CS]Cyclooxygenase Inhibitors [MoA]Nonsteroidal Anti-inflammatory Drug [EPC]

Frequently Asked Questions

Is there a manufacturer-published billing and coding guide for Combogesic?

Our team has not identified a manufacturer-published source of billing and coding information for Combogesic.

Are there any available patient assistance programs for Combogesic?

Our team has not identified a source of patient assistance information for Combogesic.

Where can I find Combogesic prescribing information?

Combogesic prescribing information can be found at the link below. Visit Here →

Is there available side effect information for Combogesic?

Our team has not identified a source of side effect information for Combogesic.

Does billing COMBOGESIC require JZ/JW wastage modifiers?

CMS does not include COMBOGESIC (J0138) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0138. For more information, visit the link below.

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