CLONIDINE HCL J Code: J0735

Drug & Product Overview

HCPCS Descriptor Injection, clonidine hydrochloride, 1 mg

HCPCS Added Date January 1, 1998

Manufacturer Multiple Manufacturers

Route of Administration Epidural, Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection, Solution | Not Available

About CLONIDINE HCL

Clonidine HCL is a medication aligned to the HCPCS J Code: J0735 for billing, pricing, and reimbursement purposes in the United States. This Non-Opioid Analgesic medication is administered via the epidural or intravenous routes and manufactured by multiple companies.

According to CMS Drug Use Information: Clonidine is used with another medication (an opioid) to treat severe pain in people with cancer. Clonidine belongs to a class of drugs known as central alpha agonists. It works by blocking the nerves in the spinal cord that send pain signals.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 4 of 6 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00143-9723-01	Clonidine Hydrochloride	Hikma Pharmaceuticals USA Inc.	5	5 MG / 10 ML
00143-9724-01	Clonidine Hydrochloride	Hikma Pharmaceuticals USA Inc.	1	1 MG / 10 ML
39822-2000-01	Clonidine	XGen Pharmaceuticals DJB, Inc.	1	1 MG / 10 ML
67457-0218-10	Duraclon	Mylan Institutional LLC	1	1 MG / 10 ML
•••••-••••-•• Log in to view	CLONIDINE HCL
	CLONIDINE HCL

Login to view 2 more NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

CLONIDINE HCL Pricing & Reimbursement

J0735 Private Payer Reimbursement

$17.41 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

CLONIDINE HCL CPT Administration Codes

CPT Code	Description
96374	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
96375	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); each additional sequential intravenous push of a new substance/drug.

JW / JZ modifiers apply

CMS has identified Clonidine HCL (J0735) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

CLONIDINE HCL Medically Unlikely Edits (MUE)

The most billing units of J0735 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient

50 units / day

= 50 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

CLONIDINE HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

severe pain in cancer patients

Drug Class

Adrenergic alpha2-Agonists [MoA]Central alpha-2 Adrenergic Agonist [EPC]

Frequently Asked Questions

Is there an available Clonidine Hcl billing and coding guide?

We have not yet identified a manufacturer source of Clonidine Hcl billing and coding information.

Are there any available Clonidine Hcl patient assistance programs?

Our team did not identify a source for Clonidine Hcl patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Clonidine Hcl prescribing information?

Our team is still working to identify a prescribing information source for CLONIDINE HCL

Where can I find Clonidine Hcl side effect information?

Our team has not yet identified a source of side effects information for CLONIDINE HCL. Please check back in a few weeks.

Does billing CLONIDINE HCL require JZ/JW wastage modifiers?

CMS has identified CLONIDINE HCL(J0735) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.