ABRYSVO CPT Vaccine Code: 90678

Vaccine & Product Overview

HCPCS Descriptor Respiratory syncytial virus vaccine, preF, subunit, bivalent, for intramuscular use

Manufacturer Pfizer

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Form Injection, Powder, Lyophilized, For Solution

About ABRYSVO

Abrysvo is a medication aligned to the HCPCS CPT Drug Code: 90678 for billing, pricing, and reimbursement purposes in the United States. It is a Vaccine drug administered via the intramuscular route and manufactured by Pfizer.

Manufacturers, reach out to us to add more information.

NDC Code Information

3 NDC packages are crosswalked to 90678. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	ABRYSVO
	ABRYSVO
	ABRYSVO

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ABRYSVO Pricing & Reimbursement

90678 Private Payer Reimbursement

$350.50 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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ABRYSVO Vaccine Administration Codes

CPT Code	Description
90471	Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections), one vaccine (single or combination vaccine/toxoid)
90472	Immunization administration (each additional vaccine or toxoid), when performed in conjunction with primary procedure.

ABRYSVO Medically Unlikely Edits (MUE)

The most billing units of 90678 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 dose.

Practitioner Office & Hospital Outpatient

1 unit / day

Same limit in both settings

MAI 2 · Date of Service Edit: Policy. Absolute per-day limit set by policy or regulation; units above it are not payable, and denials are not appealable on medical-necessity grounds. See all MUE limits →

ABRYSVO Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Respiratory syncytial virus (RSV) lower respiratory tract disease (prevention)

Frequently Asked Questions

Is there a manufacturer-published billing and coding guide for Abrysvo?

Billing and coding information for ABRYSVO can be found through PFIZER U.S.. Visit Here →

Are there any available patient assistance programs for Abrysvo?

ABRYSVO patient assistance information can be found through PFIZER U.S.. Visit Here →

Where can I find Abrysvo prescribing information?

Abrysvo prescribing information can be found at the link below. Visit Here →

Is there available side effect information for Abrysvo?

Side effect information for Abrysvo can be found through Medline Plus at the link below. Not Found →

Does billing ABRYSVO require JZ/JW wastage modifiers?

CMS does not include ABRYSVO (90678) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing 90678. For more information, visit the link below.

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