BEYFORTUS CPT Drug Code: 90380

Drug & Product Overview

HCPCS Descriptor Respiratory syncytial virus, monoclonal antibody, seasonal dose; 0.5 mL dosage, for intramuscular use

Manufacturer Sanofi

Route of Administration Intramuscular

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection

About BEYFORTUS

Beyfortus is a medication aligned to the HCPCS CPT Drug Code: 90380 for billing, pricing, and reimbursement purposes in the United States. This Vaccine medication is administered via the intramuscular route and manufactured by Sanofi.

Manufacturers, reach out to us to add more information.

NDC Code Information

2 NDC packages are crosswalked to 90380. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	BEYFORTUS
	BEYFORTUS

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BEYFORTUS Pricing & Reimbursement

90380 Private Payer Reimbursement

$635.65 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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BEYFORTUS CPT Administration Codes

CPT Code	Description
90460	Immunization administration via any route, first vaccine/toxoid component
90461	Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; each additional vaccine or toxoid component (List separately in addition to code for primary procedure).

Not on the CMS JW / JZ list

CMS does not include Beyfortus (90380) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing 90380. Wastage billing guide →

BEYFORTUS Medically Unlikely Edits (MUE)

The most billing units of 90380 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.5 ml.

Practitioner Office & Hospital Outpatient

1 unit / day

= 0.5 ml per day

MAI 2 · Date of Service Edit: Policy. Absolute per-day limit set by policy or regulation; units above it are not payable, and denials are not appealable on medical-necessity grounds. See all MUE limits →

BEYFORTUS Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

RSV lower respiratory tract disease

Drug Class

Fusion Protein Inhibitors [MoA]Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC]

Frequently Asked Questions

Is there a manufacturer-published billing and coding guide for Beyfortus?

Billing and coding information for BEYFORTUS can be found through SANOFI PASTEUR. Visit Here →

Are there any available patient assistance programs for Beyfortus?

BEYFORTUS patient assistance information can be found through SANOFI PASTEUR. Visit Here →

Where can I find Beyfortus prescribing information?

Beyfortus prescribing information can be found at the link below. Visit Here →

Is there available side effect information for Beyfortus?

Side effect information for Beyfortus can be found through Medline Plus at the link below. Visit Here →

Does billing BEYFORTUS require JZ/JW wastage modifiers?

CMS does not include BEYFORTUS (90380) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing 90380. For more information, visit the link below.

About BuyandBill.com:

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