ZERBAXA J Code: J0695

Drug & Product Overview

HCPCS Descriptor Injection, ceftolozane 50 mg and tazobactam 25 mg

HCPCS Added Date January 1, 2016

Manufacturer Merck

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About ZERBAXA

Zerbaxa is a medication aligned to the HCPCS J Code: J0695 for billing, pricing, and reimbursement purposes in the United States. Classified under Antibiotic, it is administered via the intravenous route and manufactured by Merck.

According to CMS Drug Use Information: Ceftolozane/tazobactam is used to treat a variety of bacterial infections. It is a cephalosporin antibiotic. It works by stopping the growth of bacteria.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
67919-0030-01	Zerbaxa	Merck Sharp & Dohme LLC	200	Zerbaxa Intravenous In jection 1 GM/10M… Login for More

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ZERBAXA Pricing & Reimbursement

J0695 Private Payer Reimbursement

$8.74 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

ZERBAXA CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Zerbaxa (J0695) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ZERBAXA Medically Unlikely Edits (MUE)

The most billing units of J0695 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 75mg (50mg cft/25mg taz).

Practitioner Office & Hospital Outpatient

60 units / day

= 4,500 mg (50mg cft/25mg taz) per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ZERBAXA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Complicated intra-abdominal infections Complicated urinary tract infections, including pyelonephritis Hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia

Drug Class

Cephalosporin Antibacterial [EPC]Cephalosporins [CS]beta Lactamase Inhibitor [EPC]beta Lactamase Inhibitors [MoA]

Frequently Asked Questions

Is there an available Zerbaxa billing and coding guide?

Billing and coding information for ZERBAXA can be found through Merck. Visit Here →

Are there any available Zerbaxa patient assistance programs?

ZERBAXA patient assistance information can be found through Merck. Visit Here →

Where can I find Zerbaxa prescribing information?

ZERBAXA prescribing information can be found at the link below: Visit Here →

Where can I find Zerbaxa side effect information?

Information regarding ZERBAXA's side effects can be found at MedlinePlus Visit Here →

Does billing ZERBAXA require JZ/JW wastage modifiers?

CMS has identified ZERBAXA(J0695) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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