Home › Drug Codes › J Codes › J7677 · Yupelri
Updated October 1st, 2026

Yupelri J Code: J7677

Revefenacin inhalation solution, fda-approved final product, non-compounded, administered through dme, 1 microgram

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Medicare Payment Limit ?
$0.20
up 1.0% since Q3 2026
/ HCPCS billing unitQ3 2026: $0.198
APC Payment Limit ?
Not published
CMS publishes none for Q4 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Revefenacin inhalation solution, fda-approved final product, non-compounded, administered through dme, 1 microgram
HCPCS Added Date July 1, 2019
Manufacturer Viatris
Route of Administration Inhalation
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Solution

About Yupelri

Yupelri is a medication aligned to the HCPCS J Code: J7677 for billing, pricing, and reimbursement purposes in the United States. This Respiratory medication is administered via the inhalation route and manufactured by Viatris.

According to CMS Drug Use Information: Revefenacin is a long-term medication used to treat an ongoing lung disease, chronic obstructive pulmonary disease (COPD). It must be used regularly to reduce and prevent symptoms such as shortness of breath, cough, and wheezing. This medication belongs to a class of drugs known as anticholinergics. It works by relaxing the muscles around the airways so that they open up and you can breathe more easily. Revefenacin does not work right away and should not be used to relieve sudden breathing problems. If wheezing or sudden shortness of breath occurs, use your quick-relief inhaler as prescribed.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
49502-0806-93 Yupelri Viatris Specialty LLC 5250 175 MCG / 3 ML
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Yupelri Pricing & Reimbursement

J7677 Private Payer Reimbursement
$0.20 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q4 2026

Yupelri CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
94640 Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes.
Not on the CMS JW / JZ list

CMS does not include Yupelri (J7677) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7677. Wastage billing guide →

Yupelri Medically Unlikely Edits (MUE)

The most billing units of J7677 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mcg.

Practitioner Office & Hospital Outpatient
175 units / day
= 175 mcg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mcg Enter a dose to see how many billing units it is and whether it is under the limit.

Yupelri Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chronic Obstructive Pulmonary Disease (COPD)
Drug Class
Anticholinergic [EPC]Cholinergic Antagonists [MoA]

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Compare Yupelri with alternatives

  • Yupelri J7677
  • OHTUVAYRE J7601
  • BROVANA J7605
  • PERFOROMIST J7606
  • GLYCOPYRROLATE INJECTION J1596

ASP, the Medicare payment limit, WAC and AWP for all 5 drugs on one timeline, with 10+ years of monthly history.

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Frequently Asked Questions

Is there an available Yupelri billing and coding guide?
Billing and coding information for Yupelri can be found through Mylan. Visit Here →
Are there any available Yupelri patient assistance programs?
Yupelri patient assistance information can be found through Mylan. Visit Here →
Where can I find Yupelri prescribing information?
Yupelri prescribing information can be found at the link below: Visit Here →
Where can I find Yupelri side effect information?
Information regarding Yupelri's side effects can be found at MedlinePlus Visit Here →
Does billing Yupelri require JZ/JW wastage modifiers?
CMS does not include Yupelri (J7677) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7677. For more information, visit the link below.

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