OHTUVAYRE J Code: J7601

Drug & Product Overview

HCPCS Descriptor Ensifentrine, inhalation suspension, fda approved final product, non-compounded, administered through dme, unit dose form, 3 mg

HCPCS Added Date January 1, 2025

Manufacturer Merck

Route of Administration Inhalation

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Suspension

About OHTUVAYRE

Ohtuvayre is a medication aligned to the HCPCS J Code: J7601 for billing, pricing, and reimbursement purposes in the United States. Classified under Respiratory, it is administered via the inhalation route and manufactured by Merck.

According to CMS Drug Use Information: This medication is used to treat and control symptoms (wheezing and shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema). Ensifentrine works by reducing the swelling of the airways and the muscles around the airways so you can breathe more easily. Controlling symptoms of breathing problems can decrease time lost from work or school. This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden shortness of breath or wheezing. If sudden breathing problems occur, use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) as prescribed.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
83034-0003-60	Ohtuvayre	MERCK SHARP & DOHME LLC	60	3 MG / 2.5 ML

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OHTUVAYRE Pricing & Reimbursement

J7601 Private Payer Reimbursement

$52.09 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

OHTUVAYRE CPT Administration Codes

CPT Code	Description
94640	Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes.

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

OHTUVAYRE Medically Unlikely Edits (MUE)

The most billing units of J7601 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 3 mg.

Practitioner Office

2 units / day

= 6 mg per day

Hospital Outpatient

No published MUE

Outpatient hospital · OPPS

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

OHTUVAYRE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Chronic obstructive pulmonary disease (COPD)

Drug Class

Phosphodiesterase 3 Inhibitor [EPC]Phosphodiesterase 3 Inhibitors [MoA]Phosphodiesterase 4 Inhibitor [EPC]Phosphodiesterase 4 Inhibitors [MoA]

Frequently Asked Questions

Is there an available OHTUVAYRE billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for OHTUVAYRE.

What are the available OHTUVAYRE patient assistance programs?

OHTUVAYRE patient assistance information can be found through VERONA PHARMA. Visit Here →

Where can I find OHTUVAYRE prescribing information?

OHTUVAYRE prescribing information can be found at the link below. Visit Here →

Where can I find OHTUVAYRE side effect information?

OHTUVAYRE side effect information can be found through MedlinePlus at the link below.

Does billing OHTUVAYRE require JZ/JW wastage modifiers?

CMS does not include OHTUVAYRE (J7601) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7601. For more information, visit the link below.

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