VYJUVEK J Code: J3401

Drug & Product Overview

HCPCS Descriptor Beremagene geperpavec-svdt for topical administration, containing nominal 5 x 10^9 pfu/ml vector genomes, per 0.1 ml

HCPCS Added Date January 1, 2024

Manufacturer Krystal Biotech

Route of Administration Topical application

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit

About VYJUVEK

Vyjuvek is a medication aligned to the HCPCS J Code: J3401 for billing, pricing, and reimbursement purposes in the United States. Classified under Genetic Disorder, it is administered via the topical application route and manufactured by Krystal Biotech.

Manufacturers, reach out to us to add more information.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
82194-0510-02	Vyjuvek	Krystal Biotech, Inc.	25	Kit

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VYJUVEK Pricing & Reimbursement

J3401 Private Payer Reimbursement

$1,015.86 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

VYJUVEK Medically Unlikely Edits (MUE)

The most billing units of J3401 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 ml.

Practitioner Office & Hospital Outpatient

25 units / day

= 2.5 ml per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

VYJUVEK Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Dystrophic Epidermolysis Bullosa (DEB) with mutation(s) in the COL7A1 gene

Frequently Asked Questions

Is there an available Vyjuvek billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for VYJUVEK.

Are there any available Vyjuvek patient assistance programs?

VYJUVEK patient assistance information can be found through Krystal Biotech. Visit Here →

Where can I find Vyjuvek prescribing information?

VYJUVEK prescribing information can be found at the link below: Visit Here →

Where can I find Vyjuvek side effect information?

Information regarding VYJUVEK's side effects can be found at MedlinePlus Visit Here →

Does billing VYJUVEK require JZ/JW wastage modifiers?

CMS does not include VYJUVEK (J3401) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J3401. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.