SPINRAZA J Code: J2326

Drug & Product Overview

HCPCS Descriptor Injection, nusinersen, 0.1 mg

HCPCS Added Date January 1, 2018

Manufacturer Biogen

Route of Administration Intrathecal

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Solution

About SPINRAZA

Spinraza is a medication aligned to the HCPCS J Code: J2326 for billing, pricing, and reimbursement purposes in the United States. It is a Genetic Disorder drug administered via the intrathecal route and manufactured by Biogen.

Manufacturers, reach out to us to add more information.

NDC Code Information

3 NDC packages are crosswalked to J2326. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	SPINRAZA
	SPINRAZA
	SPINRAZA

Login to view 3 NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

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SPINRAZA Pricing & Reimbursement

J2326 Private Payer Reimbursement

$1,225.01 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

SPINRAZA CPT Administration Codes

CPT Code	Description
96450	Chemotherapy administration, into CNS (eg, intrathecal), requiring and including spinal puncture

Not on the CMS JW / JZ list

CMS does not include Spinraza (J2326) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2326. Wastage billing guide →

SPINRAZA Medically Unlikely Edits (MUE)

The most billing units of J2326 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

120 units / day

= 12 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

SPINRAZA Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Spinal Muscular Atrophy (SMA)

Drug Class

Antisense Oligonucleotide [EPC]Increased Protein Synthesis [PE]OligonucleotidesAntisense [CS]Survival Motor Neuron-2-directed RNA Interaction [EPC]

Frequently Asked Questions

Is there an available Spinraza billing and coding guide?

Billing and coding information for SPINRAZA can be found through Biogen. Visit Here →

Are there any available Spinraza patient assistance programs?

SPINRAZA patient assistance information can be found through Biogen. Visit Here →

Where can I find Spinraza prescribing information?

SPINRAZA prescribing information can be found at the link below: Visit Here →

Where can I find Spinraza side effect information?

Information regarding SPINRAZA's side effects can be found at MedlinePlus Visit Here →

Does billing SPINRAZA require JZ/JW wastage modifiers?

CMS does not include SPINRAZA (J2326) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2326. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.