Home › Drug Codes › J Codes › J7674 · Provocholine
Updated July 1st, 2026

Provocholine J Code: J7674

Methacholine chloride administered as inhalation solution through a nebulizer, per 1 mg

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Q4 2026 Medicare Payment Limit for J7674, effective October 1, 2026: $1.766 per HCPCS billing unit, down 9.1% from $1.942. From CMS's final file.

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Medicare Payment Limit ?
$1.942
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
2
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Drug & Product Overview

HCPCS Descriptor Methacholine chloride administered as inhalation solution through a nebulizer, per 1 mg
HCPCS Added Date January 1, 2005
Manufacturer Methapharm
Route of Administration Inhalation
Generic Status Single-Source; Branded
Dosage Form Kit | Powder, For Solution

About Provocholine

Provocholine is a medication aligned to the HCPCS J Code: J7674 for billing, pricing, and reimbursement purposes in the United States. This Respiratory medication is administered via the inhalation route and manufactured by Methapharm.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
64281-0100-06 Provocholine Methapharm Inc. 600 100 MG
64281-0110-06 Provocholine Inhalation Solution Methapharm Inc. 384 Kit
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Provocholine Pricing & Reimbursement

J7674 Private Payer Reimbursement
$1.66 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Provocholine CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
94070 Bronchospasm provocation evaluation, multiple spirometric determinations as in 94010, with administered agents (e.g., antigen[s], cold air, methacholine)
Not on the CMS JW / JZ list

CMS does not include Provocholine (J7674) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7674. Wastage billing guide →

Provocholine Medically Unlikely Edits (MUE)

The most billing units of J7674 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mg.

Practitioner Office & Hospital Outpatient
100 units / day
= 100 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

Provocholine Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Bronchial airway hyperreactivity
Drug Class
Cholinergic Agonists [MoA]Cholinergic Receptor Agonist [EPC]

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Frequently Asked Questions

Is there an available Provocholine billing and coding guide?
Billing and coding information for Provocholine can be found through MethaPharm. Visit Here →
Are there any available Provocholine patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for Provocholine.
Where can I find Provocholine prescribing information?
Provocholine prescribing information can be found at the link below: Visit Here →
Where can I find Provocholine side effect information?
Our team has not yet identified a source of side effects information for Provocholine. Please check back in a few weeks.
Does billing Provocholine require JZ/JW wastage modifiers?
CMS does not include Provocholine (J7674) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J7674. For more information, visit the link below.

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