Home Drug Codes S Codes S0164 · PROTONIX
Updated July 1st, 2026

PROTONIX S Code: S0164

Injection, pantoprazole sodium, 40 mg

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
4
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Drug & Product Overview

HCPCS Descriptor Injection, pantoprazole sodium, 40 mg
HCPCS Added Date April 1, 2004
Manufacturer Multiple Manufacturers
Route of Administration Intravenous
Generic Status HCPCS Discontinued
Dosage Type Single-Dose
Dosage Form Injection, Powder, For Solution

About PROTONIX

Protonix is a medication aligned to the HCPCS S Code: S0164 for billing, pricing, and reimbursement purposes in the United States. Classified under Gastroenterology, it is administered via the intravenous route and manufactured by multiple companies.

Manufacturers, reach out to us to add more information.

NDC Code Information

4 NDC packages are crosswalked to S0164. Package detail is available to logged-in subscribers.

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PROTONIX CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96374 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
Not on the CMS JW / JZ list

CMS does not include Protonix (S0164) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing S0164. Wastage billing guide →

PROTONIX Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

GERD associated with a history of erosive esophagitis Pathological hypersecretory conditions including Zollinger-Ellison Syndrome pathological hypersecretory conditions including Zollinger-Ellison Syndrome
Drug Class
Proton Pump Inhibitor [EPC]Proton Pump Inhibitors [MoA]

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Frequently Asked Questions

Is there an available Protonix billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for PROTONIX.
Are there any available Protonix patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for PROTONIX.
Where can I find Protonix prescribing information?
PROTONIX prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →
Where can I find Protonix side effect information?
Our team has not yet identified a source of side effects information for PROTONIX. Please check back in a few weeks.
Does billing PROTONIX require JZ/JW wastage modifiers?
CMS does not include PROTONIX (S0164) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing S0164. For more information, visit the link below.

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