RELISTOR J Code: J2212

Self-Administered Drug Exclusion 7 Medicare Administrative Contractors list J2212 as usually self-administered and exclude it from Part B coverage in their jurisdictions. Check the article for your MAC before billing: CGS, First Coast, Noridian (A53032), Noridian (A53033), Novitas, Palmetto, Wellpoint Federal, WPS · All SAD lists →

Drug & Product Overview

HCPCS Descriptor Injection, methylnaltrexone, 0.1 mg

HCPCS Added Date January 1, 2013

Manufacturer Salix Pharmaceuticals

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Solution

About RELISTOR

Relistor is a medication aligned to the HCPCS J Code: J2212 for billing, pricing, and reimbursement purposes in the United States. It is a Gastroenterology drug administered via the subcutaneous route and manufactured by Salix Pharmaceuticals.

Manufacturers, reach out to us to add more information.

NDC Code Information

4 NDC packages are crosswalked to J2212. Package detail is available to logged-in subscribers.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
•••••-••••-•• Log in to view	RELISTOR
	RELISTOR
	RELISTOR
	RELISTOR

Login to view 4 NDC packages View pricing, complete NDC-to-HCPCS alignments, and package details.

RELISTOR Pricing & Reimbursement

J2212 Private Payer Reimbursement

$1.40 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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RELISTOR CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

JW / JZ modifiers apply

CMS has identified Relistor (J2212) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

RELISTOR Medically Unlikely Edits (MUE)

The most billing units of J2212 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 0.1 mg.

Practitioner Office & Hospital Outpatient

240 units / day

= 24 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

RELISTOR Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Opioid-Induced Constipation

Drug Class

Opioid Antagonist [EPC]Opioid Antagonists [MoA]Quaternary Ammonium Compounds [CS]

Frequently Asked Questions

Is there an available Relistor billing and coding guide?

Billing and coding information for RELISTOR can be found through Salix Pharmaceuticals. Visit Here →

Are there any available Relistor patient assistance programs?

RELISTOR patient assistance information can be found through Salix Pharmaceuticals. Visit Here →

Where can I find Relistor prescribing information?

RELISTOR prescribing information can be found at the link below: Visit Here →

Where can I find Relistor side effect information?

Information regarding RELISTOR's side effects can be found at MedlinePlus Visit Here →

Does billing RELISTOR require JZ/JW wastage modifiers?

CMS has identified RELISTOR(J2212) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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