PHENYLEPHRINE HCL J Code: J2371

Drug & Product Overview

HCPCS Descriptor Injection, phenylephrine hydrochloride, 20 micrograms

HCPCS Added Date July 1, 2023

Manufacturer Multiple Manufacturers

Route of Administration Intravenous

Generic Status Multi-Source; Generic

Dosage Type Single-Dose

Dosage Form Injection | Injection, Solution | Not Available | Solution

About PHENYLEPHRINE HCL

Phenylephrine HCL is a medication aligned to the HCPCS J Code: J2371 for billing, pricing, and reimbursement purposes in the United States. It is a Cardiology drug administered via the intravenous route and manufactured by multiple companies.

According to CMS Drug Use Information: Drug uses not available

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 85 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00641-6142-25	Phenylephrine Hydrochloride	Hikma Pharmaceuticals USA Inc.	12500	10000 MCG / 1 ML
00781-3422-92	Phenylephrine Hydrochloride	Sandoz Inc	5000	10000 MCG / 1 ML
23155-0620-41	phenylephrine hydrochloride	Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.	12500	10000 MCG / 1 ML
25021-0315-01	Phenylephrine Hydrochloride	Sagent Pharmaceuticals	12500	10000 MCG / 1 ML
42023-0214-10	Phenylephrine hydrochloride	Par Health USA, LLC	25000	50000 MCG / 5 ML
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PHENYLEPHRINE HCL Pricing & Reimbursement

J2371 Private Payer Reimbursement

$0.01 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

Phenylephrine Hydrochloride 505(b)(2) Information:

HCPCS Code	Manufacturer	Active Ingredient	HCPCS Description
J2371	Generic Code (Multiple Manufacturers)	Phenylephrine Hydrochloride	Injection, phenylephrine hydrochloride, 20 micrograms
J2372	Generic Code (Multiple Manufacturers)	Phenylephrine Hydrochloride	Injection, phenylephrine hydrochloride (biorphen), 20 micrograms
J2373	Hikma	Phenylephrine Hydrochloride	Injection, phenylephrine hydrochloride (immphentiv), 20 micrograms

PHENYLEPHRINE HCL CPT Administration Codes

CPT Code	Description
96374	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug

JW / JZ modifiers apply

CMS has identified Phenylephrine HCL (J2371) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

PHENYLEPHRINE HCL Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia Hypotension during anesthesia Hypotension resulting primarily from vasodilation in the setting of anesthesia Hypotension resulting primarily from vasodilation in the setting of septic shock clinically important hypotension resulting primarily from vasodilation clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia clinically important hypotension resulting primarily from vasodilation in the setting of septic shock hypotension during anesthesia hypotension resulting primarily from vasodilation in the setting of anesthesia hypotension resulting primarily from vasodilation in the setting of septic shock septic shock

Drug Class

Adrenergic alpha1-Agonists [MoA]alpha-1 Adrenergic Agonist [EPC]

Frequently Asked Questions

Is there an available Phenylephrine Hcl billing and coding guide?

We have not yet identified a manufacturer source of Phenylephrine Hcl billing and coding information.

Are there any available Phenylephrine Hcl patient assistance programs?

Our team did not identify a source for Phenylephrine Hcl patient assistance information. Please reach out to our team if you feel that this is a mistake.

Where can I find Phenylephrine Hcl prescribing information?

PHENYLEPHRINE HCL prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Phenylephrine Hcl side effect information?

Our team has not yet identified a source of side effects information for PHENYLEPHRINE HCL. Please check back in a few weeks.

Does billing PHENYLEPHRINE HCL require JZ/JW wastage modifiers?

CMS has identified PHENYLEPHRINE HCL(J2371) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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