NPLATE J Code: J2802

Drug & Product Overview

HCPCS Descriptor Injection, romiplostim, 1 microgram

HCPCS Added Date January 1, 2025

Manufacturer Amgen

Route of Administration Subcutaneous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Powder, Lyophilized, For Solution

About NPLATE

Nplate is a medication aligned to the HCPCS J Code: J2802 for billing, pricing, and reimbursement purposes in the United States. This Hematology medication is administered via the subcutaneous route and manufactured by Amgen.

According to CMS Drug Use Information: This medication is used to treat a certain blood disorder (idiopathic thrombocytopenia purpura - ITP) in which the blood does not clot properly due to a lack of platelets. Platelets are a type of blood cell needed to form blood clots and prevent bleeding. Romiplostim decreases your risk of bleeding by increasing the number of platelets. Romiplostim is also given to people whose ability to make platelets is reduced due to exposure to large amounts of radiation. Romiplostim acts like a certain natural substance (thrombopoietin) that causes the body to produce platelets.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 4 of 5 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
55513-0221-01	Nplate	Amgen, Inc	250	250 MCG / 0.5 ML
55513-0222-01	Nplate	Amgen, Inc	500	500 MCG / 1 ML
55513-0223-01	Nplate	Amgen, Inc	125	125 MCG / 0.25 ML
55513-0223-21	Nplate	Amgen, Inc	125	125 MCG / 0.25 ML
•••••-••••-•• Log in to view	NPLATE

Login to view 1 more NDC package View pricing, complete NDC-to-HCPCS alignments, and package details.

Login →

NPLATE Pricing & Reimbursement

J2802 Private Payer Reimbursement

$11.04 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →

Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

NPLATE Claims Performance

Claims from Jan 2026 – Aug 2026

Claim Denial Rate 60.33%

Avg. Days to File 13.0days

Avg. Days to Pay 0.0days

Real-world claims performance from FocalPoint, OnPoint Oncology's reimbursement analytics platform, with claims data accrued at the clearing house level.

Explore J2802 claims analytics on FocalPoint →

NPLATE CPT Administration Codes

CPT Code	Description
96372	Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); intramuscular

Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

NPLATE Medically Unlikely Edits (MUE)

The most billing units of J2802 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 mcg.

Practitioner Office & Hospital Outpatient

1,500 units / day

= 1,500 mcg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

NPLATE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Hematopoietic Syndrome of Acute Radiation Syndrome (H-ARS) Immune Thrombocytopenia (ITP)

Drug Class

Increased Megakaryocyte Maturation [PE]Increased Platelet Production [PE]Thrombopoietin Receptor Agonist [EPC]Thrombopoietin Receptor Agonists [MoA]

Frequently Asked Questions

Is there an available NPLATE billing and coding guide?

Billing and coding information for NPLATE can be found through Amgen Inc. Visit Here →

What are the available NPLATE patient assistance programs?

NPLATE patient assistance information can be found through Amgen Inc. Visit Here →

Where can I find NPLATE prescribing information?

NPLATE prescribing information can be found at the link below. Visit Here →

Where can I find NPLATE side effect information?

NPLATE side effect information can be found through MedlinePlus at the link below.

Does billing NPLATE require JZ/JW wastage modifiers?

CMS does not include NPLATE (J2802) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J2802. For more information, visit the link below.

About BuyandBill.com:

The BuyandBill.com team is dedicated to delivering high-quality coding and billing information for office-administered drugs. We continuously research HCPCS-coded medications to expand our resources and ensure data accuracy. Manufacturers: click here to sponsor your medication, and we will ensure the most accurate and detailed information is displayed.