Home › Drug Codes › Q Codes › Q9967 · ISOVUE-300
Updated July 1st, 2026

ISOVUE-300 Q Code: Q9967

Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml

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Q4 2026 Medicare Payment Limit for Q9967, effective October 1, 2026: $0.186 per HCPCS billing unit, up 20.0% from $0.155. From CMS's final file.

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Medicare Payment Limit ?
$0.155
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
114
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Drug & Product Overview

HCPCS Descriptor Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml
HCPCS Added Date January 1, 2008
Manufacturer Multiple Manufacturers
Route of Administration Intra-Arterial, Intra-Articular, Intrathecal, Intravascular, Intravenous, Oral, Rectal
Generic Status Multi-Source; Generic
Dosage Type Single-Dose, Multi-Dose
Dosage Form Injection | Injection, Solution

About ISOVUE-300

Isovue-300 is a medication aligned to the HCPCS Q Code: Q9967 for billing, pricing, and reimbursement purposes in the United States. Classified under Imaging/Radiopharmaceutical, it is administered via the intra-arterial, intra-articular, intrathecal, intravascular, intravenous, oral, or rectal routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used before X-ray imaging tests (such as CT scans). Iohexol contains iodine and belongs to a class of drugs known as contrast media or dyes. It works by adding contrast to body parts and fluids in these imaging tests. Iohexol improves the images obtained during a CT scan, so your doctor can more easily diagnose your condition.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 114 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00019-1323-06 Optiray 320 Liebel-Flarsheim Company LLC 1250 33900 MG / 50 ML
00270-1315-25 Isovue 300 BRACCO DIAGNOSTICS INC 300 18360 MG / 30 ML
00270-1316-52 Isovue-370 Bracco Diagnostics Inc. 750 Isovue-370 Intravenous Solution 76 % -… Login for More
00407-1413-10 Omnipaque GE Healthcare Inc. 100 3000 MG / 10 ML
00407-1413-72 Omnipaque GE Healthcare 5000 150000 MG / 500 ML
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ISOVUE-300
ISOVUE-300
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ISOVUE-300 Pricing & Reimbursement

Q9967 Private Payer Reimbursement
$0.23 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

ISOVUE-300 CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96374 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Login for More Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure) Login for More
Not on the CMS JW / JZ list

CMS does not include Isovue-300 (Q9967) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q9967. Wastage billing guide →

ISOVUE-300 Medically Unlikely Edits (MUE)

The most billing units of Q9967 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 ml.

Practitioner Office & Hospital Outpatient
300 units / day
= 300 ml per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ml Enter a dose to see how many billing units it is and whether it is under the limit.

ISOVUE-300 Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Angiocardiography Angiocardiography (left ventriculography and selective coronary arteriography) Angiocardiography (left ventriculography and selective coronary arteriography), peripheral arteriography, visceral arteriography, and cerebral arteriography Angiocardiography, cerebral arteriography, and visceral arteriography Angiocardiography, cerebral arteriography, visceral arteriography Aortic Root and Arch Study Aortography Aortography and Selective Visceral Arteriography Arthrography CT Cisternography CT Imaging of the Body CT Imaging of the Head CT Imaging of the Head and Body CT cisternography CT imaging of the body CT imaging of the head CT imaging of the head and body CT of the Abdomen and Pelvis CT of the Body CT of the Head CT of the Head and Body Cardiac Ventriculography Cerebral Arteriography Cerebral arteriography Cervical Myelography Cervical myelography Cervical myelography and CT myelography Computed Tomography (CT) of the Body Computed Tomography (CT) of the Head Computed Tomography (CT) of the Head and Body Contrast CT of the body Contrast CT of the head Contrast CT of the head and body Contrast mammography Coronary Arteriography and Cardiac Ventriculography Coronary Arteriography and Left Ventriculography Coronary arteriography and left ventriculography Coronary computed tomography angiography (CCTA) Endoscopic Retrograde Pancreatography (ERP) and Cholangiopancreatography (ERCP) Excretory Urography Excretory urography Herniography Hysterosalpingography Intra-arterial Digital Subtraction Angiography (IA-DSA) Intra-arterial digital subtraction angiography (IA-DSA) Intravenous Digital Subtraction Angiography Intravenous Digital Subtraction Angiography (IV-DSA) Intravenous Excretory Urography Intravenous digital subtraction angiography (IV-DSA) Intravenous excretory urography Lumbar Myelography Lumbar and thoracic myelography Lumbar and thoracic myelography, and CT myelography Myelography (Lumbar, Thoracic, Cervical, Total Columnar) and CT Cisternography Myelography (pediatric) Peripheral Arteriography Peripheral Arteriography — Aortofemoral Runoffs Peripheral Arteriography — Selective Arteriogram Peripheral Venography Peripheral Venography (Phlebography) Peripheral arteriography Peripheral venography Pulmonary Angiography Radiographic Examination of the GI Tract Radiographic Examination of the Gastrointestinal (GI) Tract Radiographic evaluation of cardiac chambers and related arteries Selective Coronary Arteriography Selective Visceral Arteriography and Aortography Thoracic Myelography Total Columnar Myelography Total columnar myelography Total columnar myelography and CT myelography Venography Visceral and Renal Arteriography and Aortography Visceral and renal arteriography and aortography Visceral angiography and aortography Visceral arteriography Voiding Cystourethrography (VCU)
Drug Class
Radiographic Contrast Agent [EPC]X-Ray Contrast Activity [MoA]

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Frequently Asked Questions

Is there an available Isovue-300 billing and coding guide?
We have not yet identified a manufacturer source of Isovue-300 billing and coding information.
Are there any available Isovue-300 patient assistance programs?
Our team did not identify a source for Isovue-300 patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Isovue-300 prescribing information?
Our team is still working to identify a prescribing information source for ISOVUE-300
Where can I find Isovue-300 side effect information?
Our team has not yet identified a source of side effects information for ISOVUE-300. Please check back in a few weeks.
Does billing ISOVUE-300 require JZ/JW wastage modifiers?
CMS does not include ISOVUE-300 (Q9967) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q9967. For more information, visit the link below.

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