Home › Drug Codes › Q Codes › Q9966 · ISOVUE-200
Updated July 1st, 2026

ISOVUE-200 Q Code: Q9966

Low osmolar contrast material, 200-299 mg/ml iodine concentration, per ml

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Q4 2026 Medicare Payment Limit for Q9966, effective October 1, 2026: $0.421 per HCPCS billing unit, down 3.2% from $0.435. From CMS's final file.

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Medicare Payment Limit ?
$0.435
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
21
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Drug & Product Overview

HCPCS Descriptor Low osmolar contrast material, 200-299 mg/ml iodine concentration, per ml
HCPCS Added Date January 1, 2008
Manufacturer Multiple Manufacturers
Route of Administration Intra-Articular, Intrathecal, Intravascular, Intravenous, Oral, Rectal
Generic Status Multi-Source; Generic
Dosage Type Single-Dose
Dosage Form Injection, Solution

About ISOVUE-200

Isovue-200 is a medication aligned to the HCPCS Q Code: Q9966 for billing, pricing, and reimbursement purposes in the United States. It is an Imaging/Radiopharmaceutical drug administered via the intra-articular, intrathecal, intravascular, intravenous, oral, or rectal routes and manufactured by multiple companies.

According to CMS Drug Use Information: This medication is used before X-ray imaging tests (such as CT scans). Iohexol contains iodine and belongs to a class of drugs known as contrast media or dyes. It works by adding contrast to body parts and fluids in these imaging tests. Iohexol improves the images obtained during a CT scan, so your doctor can more easily diagnose your condition.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 21 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00270-1314-15 Isovue 200 BRACCO DIAGNOSTICS INC 2000 81600 MG / 200 ML
00270-1317-02 Isovue 250 BRACCO DIAGNOSTICS INC 1000 51000 MG / 100 ML
00407-1412-10 Omnipaque GE Healthcare Inc. 100 2400 MG / 10 ML
65219-0381-10 Iodixanol FRESENIUS KABI USA, LLC 1000 27000 MG / 100 ML
70436-0124-52 iopamidol Slate Run Pharmaceuticals, LLC 200 81600 MG / 200 ML
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ISOVUE-200
ISOVUE-200
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ISOVUE-200 Pricing & Reimbursement

Q9966 Private Payer Reimbursement
$0.70 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

ISOVUE-200 CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96374 Therapeutic, prophylactic, or diagnostic injection (specify substance or drug), IV push, single, or initial substance/drug
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
Not on the CMS JW / JZ list

CMS does not include Isovue-200 (Q9966) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q9966. Wastage billing guide →

ISOVUE-200 Medically Unlikely Edits (MUE)

The most billing units of Q9966 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 ml.

Practitioner Office & Hospital Outpatient
250 units / day
= 250 ml per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ml Enter a dose to see how many billing units it is and whether it is under the limit.

ISOVUE-200 Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Angiocardiography Angiocardiography (left ventriculography and selective coronary arteriography) Angiocardiography (left ventriculography and selective coronary arteriography), peripheral arteriography, visceral arteriography, and cerebral arteriography Angiocardiography, cerebral arteriography, and visceral arteriography Aortic Root and Arch Study Aortography Aortography and Selective Visceral Arteriography Arthrography CT Cisternography CT cisternography CT imaging of the head and body CT of the Abdomen and Pelvis CT of the Body CT of the Head CT of the Head and Body Cardiac Ventriculography Cerebral Arteriography Cerebral arteriography Cervical Myelography Cervical myelography Cervical myelography and CT myelography Computed Tomography (CT) of the Body Computed Tomography (CT) of the Head Computed Tomography (CT) of the Head and Body Coronary Arteriography and Cardiac Ventriculography Coronary computed tomography angiography (CCTA) Endoscopic Retrograde Pancreatography (ERP) and Cholangiopancreatography (ERCP) Excretory Urography Excretory urography Herniography Hysterosalpingography Intra-arterial Digital Subtraction Angiography (IA-DSA) Intra-arterial digital subtraction angiography (IA-DSA) Intravenous Digital Subtraction Angiography (IV-DSA) Lumbar Myelography Lumbar and thoracic myelography Lumbar and thoracic myelography, and CT myelography Myelography (Lumbar, Thoracic, Cervical, Total Columnar) and CT Cisternography Peripheral Arteriography Peripheral Arteriography — Aortofemoral Runoffs Peripheral Arteriography — Selective Arteriogram Peripheral Venography Peripheral Venography (Phlebography) Peripheral arteriography Peripheral venography Pulmonary Angiography Radiographic Examination of the GI Tract Selective Coronary Arteriography Selective Visceral Arteriography and Aortography Thoracic Myelography Total Columnar Myelography Total columnar myelography Total columnar myelography and CT myelography Visceral arteriography Voiding Cystourethrography (VCU)
Drug Class
Radiographic Contrast Agent [EPC]X-Ray Contrast Activity [MoA]

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Frequently Asked Questions

Is there an available Isovue-200 billing and coding guide?
We have not yet identified a manufacturer source of Isovue-200 billing and coding information.
Are there any available Isovue-200 patient assistance programs?
Our team did not identify a source for Isovue-200 patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Isovue-200 prescribing information?
Our team is still working to identify a prescribing information source for ISOVUE-200
Where can I find Isovue-200 side effect information?
Our team has not yet identified a source of side effects information for ISOVUE-200. Please check back in a few weeks.
Does billing ISOVUE-200 require JZ/JW wastage modifiers?
CMS does not include ISOVUE-200 (Q9966) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing Q9966. For more information, visit the link below.

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