ELLENCE J Code: J9178

Drug & Product Overview

HCPCS Descriptor Injection, epirubicin hcl, 2 mg

HCPCS Added Date January 1, 2004

Manufacturer Pfizer

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Injection, Solution

About ELLENCE

Ellence is a medication aligned to the HCPCS J Code: J9178 for billing, pricing, and reimbursement purposes in the United States. It is an Oncology drug administered via the intravenous route and manufactured by Pfizer.

According to CMS Drug Use Information: Epirubicin is used to treat breast cancer. It belongs to a class of drugs known as anthracyclines and works by slowing or stopping the growth of cancer cells.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. The list of NDCs below is not exhaustive.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
00009-5091-01	Ellence	Pfizer Inc	25	50 MG / 25 ML
00009-5091-25	Ellence	Pharmacia & Upjohn Company LLC	25	50 MG / 25 ML
00009-5093-01	Ellence	Pfizer Inc	100	200 MG / 100 ML
00009-5093-10	Ellence	Pharmacia & Upjohn Company LLC	100	200 MG / 100 ML

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ELLENCE Pricing & Reimbursement

J9178 Private Payer Reimbursement

$1.82 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q3 2026

ELLENCE CPT Administration Codes

CPT Code	Description
96413	Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
96415	Chemotherapy administration, intravenous infusion technique; each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Ellence (J9178) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ELLENCE Medically Unlikely Edits (MUE)

The most billing units of J9178 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 2 mg.

Practitioner Office & Hospital Outpatient

150 units / day

= 300 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ELLENCE Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Breast cancer with axillary node tumor involvement following resection

Drug Class

Anthracycline Topoisomerase Inhibitor [EPC]Anthracyclines [CS]Topoisomerase Inhibitors [MoA]

Frequently Asked Questions

Is there an available Ellence billing and coding guide?

Our team has not identified a manufacturer-published source of billing and coding information for ELLENCE.

Are there any available Ellence patient assistance programs?

Our team has not identified a manufacturer-published source of patient assistance information for ELLENCE.

Where can I find Ellence prescribing information?

ELLENCE prescribing information can be found at the link below. Please reach out to us if you believe this information to be innacurate or out of date. Visit Here →

Where can I find Ellence side effect information?

Our team has not yet identified a source of side effects information for ELLENCE. Please check back in a few weeks.

Does billing ELLENCE require JZ/JW wastage modifiers?

CMS has identified ELLENCE(J9178) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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