Home › Drug Codes › J Codes › J0688 · CEFAZOLIN
Updated July 1st, 2026

CEFAZOLIN J Code: J0688

Injection, cefazolin sodium (hikma), not therapeutically equivalent to j0690, 500 mg

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Q4 2026 Medicare Payment Limit for J0688, effective October 1, 2026: $0.829 per HCPCS billing unit, down 2.1% from $0.847. From CMS's final file.

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Medicare Payment Limit ?
$0.847
/ HCPCS billing unit · Q3 2026
APC Payment Limit ?
Not published
CMS publishes none for Q3 2026
ASP ?
$•••.••
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WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
4
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Drug & Product Overview

HCPCS Descriptor Injection, cefazolin sodium (hikma), not therapeutically equivalent to j0690, 500 mg
HCPCS Added Date January 1, 2024
Manufacturer Hikma
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Type Single-Dose
Dosage Form Injection, Powder, For Solution

About CEFAZOLIN

Cefazolin is a medication aligned to the HCPCS J Code: J0688 for billing, pricing, and reimbursement purposes in the United States. It is an Antibiotic drug administered via the intravenous route and manufactured by Hikma.

According to CMS Drug Use Information: Cefazolin is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain surgeries to help prevent infection. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 2 of 4 NDCs — log in for the full crosswalk.

NDC Code Drug Manufacturer Billing Units / Pkg Package Size
00143-9139-25 Cefazolin Hikma Pharmaceuticals USA Inc. 100 Cefazolin Intravenous Injection 2 G/1 … Login for More
00143-9140-25 Cefazolin Hikma Pharmaceuticals USA Inc. 150 Cefazolin Intravenous Injection 3 G/1 … Login for More
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CEFAZOLIN
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CEFAZOLIN Pricing & Reimbursement

J0688 Private Payer Reimbursement
$0.95 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

Create an account on PayerPrice for more information →
UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

Historical Graphing and Billing Calculator

per HCPCS unit
As of Q3 2026

Cefazolin Sodium 505(b)(2) Information:

HCPCS Code Manufacturer Active Ingredient HCPCS Description
J0687 WG Critical Care Cefazolin Sodium Injection, cefazolin sodium (wg critical care), not therapeutically equivalent to j0690, 500 mg
J0688 Hikma Cefazolin Sodium Injection, cefazolin sodium (hikma), not therapeutically equivalent to j0690, 500 mg
J0689 Baxter Healthcare Cefazolin Sodium Injection, cefazolin sodium (baxter), not therapeutically equivalent to j0690, 500 mg
J0690 Generic Code (Multiple Manufacturers) Cefazolin Sodium Injection, cefazolin sodium, 500 mg

CEFAZOLIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96365 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366 Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)
Not on the CMS JW / JZ list

This product is new and does not yet appear on the CMS list of HCPCS pertaining to single-dose containers. Wastage billing guide →

CEFAZOLIN Medically Unlikely Edits (MUE)

The most billing units of J0688 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 500 mg.

Practitioner Office & Hospital Outpatient
16 units / day
= 8,000 mg per day

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

mg Enter a dose to see how many billing units it is and whether it is under the limit.

CEFAZOLIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Biliary Tract Infections Bone and Joint Infections Endocarditis Genital Infections Perioperative Prophylaxis Respiratory Tract Infections Septicemia Skin and Skin Structure Infections Urinary Tract Infections
Drug Class
Cephalosporin Antibacterial [EPC]Cephalosporins [CS]

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Frequently Asked Questions

Is there an available Cefazolin billing and coding guide?
We have not yet identified a manufacturer source of Cefazolin billing and coding information.
Are there any available Cefazolin patient assistance programs?
Our team did not identify a source for Cefazolin patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Cefazolin prescribing information?
CEFAZOLIN prescribing information can be found at the link below: Visit Here →
Where can I find Cefazolin side effect information?
Information regarding CEFAZOLIN's side effects can be found at MedlinePlus Visit Here →
Does billing CEFAZOLIN require JZ/JW wastage modifiers?
CMS does not include CEFAZOLIN (J0688) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J0688. For more information, visit the link below.

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Related Drug Codes

Explore billing, coding, and pricing for drugs related to CEFAZOLIN.

J0690CEFAZOLINInjection, cefazolin sodium, 500 mgMultiple ManufacturersAdded January 1, 1982J0687CefazolinInjection, cefazolin sodium (wg critical care), not therapeutically equivalent to j0690, 500 mgWG Critical CareAdded July 1, 2024J0525CEFOTETAN DISODIUMInjection, cefotetan disodium, 10 mgMultiple ManufacturersAdded October 1, 2025J0689Cefazolin SodiumInjection, cefazolin sodium (baxter), not therapeutically equivalent to j0690, 500 mgBaxter HealthcareAdded January 1, 2023J0694CEFOXITINInjection, cefoxitin sodium, 1 gmMultiple ManufacturersAdded January 1, 1992J0696CEFTRIAXONEInjection, ceftriaxone sodium, per 250 mgMultiple ManufacturersAdded January 1, 1990J0697CEFUROXIME SODIUMInjection, sterile cefuroxime sodium, per 750 mgMultiple ManufacturersAdded January 1, 1990J0290AmpicillinInjection, ampicillin sodium, 500 mgMultiple ManufacturersAdded January 1, 1984J0737CLINDAMYCIN PHOSPHATE IN NACLInjection, clindamycin phosphate (baxter), not therapeutically equivalent to j0736, 300 mgBaxter HealthcareAdded July 1, 2023J0743IMIPENEM-CILASTATIN SODIUMInjection, cilastatin sodium; imipenem, per 250 mgMultiple ManufacturersAdded January 1, 1993