ALTUVIIIO J Code: J7214

Drug & Product Overview

HCPCS Descriptor Injection, factor viii/von willebrand factor complex, recombinant (altuviiio), per factor viii i.u.

HCPCS Added Date October 1, 2023

Manufacturer Sanofi

Route of Administration Intravenous

Generic Status Single-Source; Branded

Dosage Type Single-Dose

Dosage Form Kit | Not Available

About ALTUVIIIO

Altuviiio is a medication aligned to the HCPCS J Code: J7214 for billing, pricing, and reimbursement purposes in the United States. Classified under Hematology, it is administered via the intravenous route and manufactured by Sanofi.

According to CMS Drug Use Information: This medication is used to control and prevent bleeding that happens to people (usually males) with an inherited medical condition, hemophilia A (low levels of factor VIII). It is also given before surgery to prevent too much bleeding in people with this condition. Factor VIII is a protein (clotting factor) that is in normal blood, and helps form blood clots and stop bleeding after an injury. People with low factor VIII levels may bleed longer than normal after an injury/surgery and may have bleeding inside the body (especially in the joints and muscles). This medication contains man-made factor VIII (antihemophilic factor) to temporarily replace factor VIII in the body, connected to an antibody (immunoglobulin) that helps the man-made factor VIII work longer. When used to control and prevent bleeding, this medication may help relieve pain and long-term damage caused by hemophilia A. This medication should not be used to treat von Willebrand disease.

Disclaimer: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your healthcare professional.

NDC Code Information

Based on publicly available CMS files. Showing 5 of 12 NDCs — log in for the full crosswalk.

NDC Code	Drug	Manufacturer	Billing Units / Pkg	Package Size
71104-0978-01	Altuviiio	Bioverativ Therapeutics Inc.	1	Kit
71104-0979-01	Altuviiio	Bioverativ Therapeutics Inc.	1	Kit
71104-0981-01	Altuviiio	Bioverativ Therapeutics Inc.	1	Kit
71104-0982-01	Altuviiio	Bioverativ Therapeutics Inc.	1	Kit
71104-0983-01	Altuviiio	Bioverativ Therapeutics Inc.	1	Kit
•••••-••••-•• Log in to view	ALTUVIIIO
	ALTUVIIIO
	ALTUVIIIO

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ALTUVIIIO Pricing & Reimbursement

J7214 Private Payer Reimbursement

$4.49 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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Historical Graphing and Billing Calculator

per HCPCS unit

As of Q4 2026

ALTUVIIIO CPT Administration Codes

CPT Code	Description
96365	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); initial, up to 1 hour
96366	Intravenous infusion, for therapy, prophylaxis, or diagnosis (specify substance or drug); each additional hour (List separately in addition to code for primary procedure)

JW / JZ modifiers apply

CMS has identified Altuviiio (J7214) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. Wastage billing guide →

ALTUVIIIO Medically Unlikely Edits (MUE)

The most billing units of J7214 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 1 iu. The limit is different in the office and the hospital. Use the one for your setting.

Practitioner Office

7,500 units / day

= 7,500 iu per day

Hospital Outpatient

9,600 units / day

= 9,600 iu per day

MAI 1 · Line Edit. Per-line limit: units are checked per claim line; medically necessary units beyond the limit may be billable on separate lines with appropriate modifiers. See all MUE limits →

ALTUVIIIO Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Hemophilia A (congenital factor VIII deficiency)

Frequently Asked Questions

Is there an available Altuviiio billing and coding guide?

Billing and coding information for ALTUVIIIO can be found through BIOVERATIV THERAPEUTICS. Visit Here →

Are there any available Altuviiio patient assistance programs?

ALTUVIIIO patient assistance information can be found through BIOVERATIV THERAPEUTICS. Visit Here →

Where can I find Altuviiio prescribing information?

ALTUVIIIO prescribing information can be found at the link below: Visit Here →

Where can I find Altuviiio side effect information?

Our team has not yet identified a source of side effects information for ALTUVIIIO. Please check back in a few weeks.

Does billing ALTUVIIIO require JZ/JW wastage modifiers?

CMS has identified ALTUVIIIO(J7214) as a HCPCS code with single-dose containers. Therefore, the JW/JZ wastage modifiers could be required for billing purposes. See CMS guidelines on use of the JZ and JW wastage modifiers below.

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