Home › Drug Codes › J Codes › J9215 · ALFERON N
Updated October 1st, 2026

ALFERON N J Code: J9215

Injection, interferon, alfa-n3, (human leukocyte derived), 250,000 iu

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Medicare Payment Limit ?
Not published
CMS publishes none for Q4 2026
APC Payment Limit ?
Not published
CMS publishes none for Q4 2026
ASP ?
No current ASP
Not available for Q4 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Injection, interferon, alfa-n3, (human leukocyte derived), 250,000 iu
HCPCS Added Date January 1, 1993
Manufacturer HEMISPHERX BIOPHARMA, INC.
Route of Administration Injection
Generic Status Single-Source; Branded

About ALFERON N

Alferon N is a medication aligned to the HCPCS J Code: J9215 for billing, pricing, and reimbursement purposes in the United States. Classified under Immunology, it is administered via the injection route and manufactured by HEMISPHERX BIOPHARMA, INC.

Manufacturers, reach out to us to add more information.

NDC Code Information

1 NDC package is crosswalked to J9215. Package detail is available to logged-in subscribers.

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ALFERON N Pricing & Reimbursement

J9215 Private Payer Reimbursement
$31.11 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

ALFERON N CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
96401 Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic
Not on the CMS JW / JZ list

CMS does not include Alferon N (J9215) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9215. Wastage billing guide →

ALFERON N Medically Unlikely Edits (MUE)

The most billing units of J9215 Medicare will pay for one patient in one day, as published by CMS. 1 unit = 250,000 iu.

Practitioner Office & Hospital Outpatient
0 units / day
Not payable in this setting

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

,000 iu Enter a dose to see how many billing units it is and whether it is under the limit.

ALFERON N Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

External condylomata acuminata (genital warts)

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Frequently Asked Questions

Is there an available Alferon N billing and coding guide?
We have not yet identified a manufacturer source of Alferon N billing and coding information.
Are there any available Alferon N patient assistance programs?
Our team did not identify a source for Alferon N patient assistance information. Please reach out to our team if you feel that this is a mistake.
Where can I find Alferon N prescribing information?
ALFERON N prescribing information can be found at the link below: Visit Here →
Where can I find Alferon N side effect information?
Information regarding ALFERON N's side effects can be found at MedlinePlus Visit Here →
Does billing ALFERON N require JZ/JW wastage modifiers?
CMS does not include ALFERON N (J9215) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing J9215. For more information, visit the link below.

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