Home Drug Codes A Codes A9543 · ZEVALIN
Updated July 1st, 2026

ZEVALIN A Code: A9543

Yttrium y-90 ibritumomab tiuxetan, therapeutic, per treatment dose, up to 40 millicuries

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Medicare Payment Limit ?
Not published
CMS publishes none for Q3 2026
APC Payment Limit ?
$56,824.549
/ HCPCS billing unit · APC 1643
ASP ?
No current ASP
Not available for Q3 2026
WAC · AWP ?
$•••.••
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NDCs Crosswalked ?
1
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Drug & Product Overview

HCPCS Descriptor Yttrium y-90 ibritumomab tiuxetan, therapeutic, per treatment dose, up to 40 millicuries
HCPCS Added Date January 1, 2006
Manufacturer Acrotech Biopharma
Route of Administration Intravenous
Generic Status Single-Source; Branded
Dosage Form Kit

About ZEVALIN

Zevalin is a medication aligned to the HCPCS A Code: A9543 for billing, pricing, and reimbursement purposes in the United States. This Imaging/Radiopharmaceutical medication is administered via the intravenous route and manufactured by Acrotech Biopharma.

Manufacturers, reach out to us to add more information.

NDC Code Information

1 NDC package is crosswalked to A9543. Package detail is available to logged-in subscribers.

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ZEVALIN Pricing & Reimbursement

A9543 Private Payer Reimbursement
$68,175.84 / HCPCS unit as of Jan 2026

National median reimbursement across major commercial payers.

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UnitedHealthcare, BlueCross BlueShield, Aetna, Cigna

ZEVALIN CPT Administration Codes

The below list of CPT codes is intended for informational purposes only and may not be exhaustive. CPT® codes and descriptions are copyright American Medical Association (AMA). All rights reserved.

CPT Code Description
79101 Radiopharmaceutical therapy, by intravenous administration
Not on the CMS JW / JZ list

CMS does not include Zevalin (A9543) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing A9543. Wastage billing guide →

ZEVALIN Medically Unlikely Edits (MUE)

The most billing units of A9543 Medicare will pay for one patient in one day, as published by CMS. 1 unit = up to 40 millicuries.

Practitioner Office & Hospital Outpatient
1 unit / day
Same limit in both settings

MAI 3 · Date of Service Edit: Clinical. Per-day limit based on clinical expectations; excess units are denied but may be appealed with documentation of medical necessity. See all MUE limits →

ZEVALIN Clinical Information

Indications and drug classification.

Treated Diseases & Conditions

This list of indications is not exhaustive and may be subject to errors. The information on BuyandBill.com is intended for informational purposes only and should not be used for medical advice.

Follicular Non-Hodgkin'S Lymphoma Refractory Follicular Non-Hodgkin'S Lymphoma Relapsed Follicular B-Cell Non-Hodgkin'S Lymphoma

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Frequently Asked Questions

Is there an available Zevalin billing and coding guide?
Our team has not identified a manufacturer-published source of billing and coding information for ZEVALIN.
Are there any available Zevalin patient assistance programs?
Our team has not identified a manufacturer-published source of patient assistance information for ZEVALIN.
Where can I find Zevalin prescribing information?
ZEVALIN prescribing information can be found at the link below: Visit Here →
Where can I find Zevalin side effect information?
Information regarding ZEVALIN's side effects can be found at MedlinePlus Visit Here →
Does billing ZEVALIN require JZ/JW wastage modifiers?
CMS does not include ZEVALIN (A9543) on its list of HCPCS pertaining to single-dose containers. Per CMS guidelines, the JZ/JW wastage modifiers may not apply when billing A9543. For more information, visit the link below.

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