CPT Administration Code: 79101 | Radiopharmaceutical Therapy

Code Overview

CPT® administration code details for 79101.

CPT Code Descriptor Radiopharmaceutical therapy, by intravenous administration

Code Category Radiopharmaceutical Therapy

Route / Technique Intravenous Injection

Code Type Initial / Primary Code

About Radiopharmaceutical Therapy – 79101

79101 is a CPT administration code for radiopharmaceutical therapy. The description for 79101: Radiopharmaceutical therapy, by intravenous administration.

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79101 RVU Breakdown & Medicare Reimbursement

Based on the CY 2026 CMS Physician Fee Schedule. National payment amounts, before geographic (GPCI) adjustment.

Component	Facility	Non-Facility
Work RVU — physician work	1.91	1.91
Practice Expense RVU — staff, supplies, equipment	2.28	2.28
Malpractice RVU — professional liability	0.09	0.09
Total RVUs	4.28	4.28
Medicare Payment — Total RVUs × $33.4009 CF	$142.96	$142.96

CY 2026 Medicare Conversion Factor: $33.4009. Facility and non-facility practice-expense RVUs are equal for this code.

79101 Locality-Adjusted Rates

Medicare payment varies by locality via GPCI adjustment. Log in to view rates for all 100+ Medicare localities.

Medicare Locality	Facility	Non-Facility
National (unadjusted)	$142.96	$142.96
Los Angeles–Long Beach, CA
Manhattan, NY
Houston, TX
Miami, FL

Drugs Commonly Billed with 79101

HCPCS-coded drugs frequently administered under this CPT code. The list below is not exhaustive.

HCPCS Code	Drug	HCPCS Descriptor
A9513	LUTATHERA	Lutetium lu 177, dotatate, therapeutic, 1 millicurie
A9607	PLUVICTO	Lutetium lu 177 vipivotide tetraxetan, therapeutic, 1 millicurie
A9604	QUADRAMET	Samarium sm-153 lexidronam, therapeutic, per treatment dose, up to 150 millicuries
A9600	STRONTIUM CHLORIDE SR 89	Strontium sr-89 chloride, therapeutic, per millicurie
A9543	ZEVALIN	Yttrium y-90 ibritumomab tiuxetan, therapeutic, per treatment dose, up to 40 millicuries

Frequently Asked Questions

What are CPT Administration Codes?

CPT administration codes cover the work of giving a drug to a patient, such as an injection or an infusion. The drug itself is billed with its HCPCS J-code, and the administration is billed with a CPT code. Both go on the same claim. Learn More →

What is the Medicare Conversion Factor?

The conversion factor is the dollar amount CMS uses to turn a code's total RVUs into a Medicare payment. This page uses the CY 2026 conversion factor of $33.4009. CMS updates it every year in the Physician Fee Schedule final rule.

Facility vs. Non-Facility?

The non-facility rate applies in a physician office, where the practice pays for its own staff, supplies, and equipment, so the rate is usually higher. The facility rate applies in hospital outpatient departments and ASCs, where the facility bills for those costs separately.

How do I decide which administration code to use?

Pick the code that matches the type of drug, the route, and how long the administration takes. Start from the highest-ranking service you performed, then add the appropriate add-on codes for extra time or extra drugs. Manufacturer billing and coding guides often list suggested administration codes.

About BuyandBill.com:

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CPT Administration Code: 79101 – Radiopharmaceutical Therapy